Cellular Resilience

Some of your organs could be aging faster than the rest of your body

Today I’m with functional medicine expert, bestselling author, and repeat guest Dr. Will Cole to explore why your cells may be aging faster than your chronological age suggests. We unpack the everyday factors that can create cellular confusion, from metabolic dysfunction and environmental toxins to disrupted light exposure, chronic stress, and the foods you eat, then explore practical ways to rebuild resilience through nutrition, fasting, nature, sleep, and targeted therapies. Most importantly, I want you to come away knowing that you do not need a perfect routine to change your trajectory because small choices that consistently love your body back can make a powerful difference.

What you’ll learn:

(04:48) Dr. Will Cole shares insights from a Stanford study revealing that one in five adults over age 50 has an organ aging significantly faster than the rest of their body.

(09:50) Why individuals born after 1965 and younger generations like Gen Z are experiencing accelerated cellular aging and biological decline.

(17:39) The major modern drivers of cellular confusion, including environmental toxins, blue light pollution, and unresolved trauma.

(23:52) Key foundational lab markers you should test to accurately evaluate your metabolic health and cellular aging rate.

(26:44) How healthy fats and compounds like C15 protect your cell membranes from cellular fragility syndrome.

(28:31) How xenohormetic plant foods and adversity mimetics train your cells to build true resilience.

(40:15) How to customize your fasting routine to activate cellular recycling pathways without overtaxing your body.

(46:29) The therapeutic benefits, potential pitfalls, and emotional side effects of peptides and GLP-1 agonists.

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Resources Mentioned in this episode

Learn more about Dr. Will Cole on their website, https://drwillcole.com/ 

Dr. Cole’s Podcast “The Art of Being Well”

Heal Your Cells BOOK

Previous Episode with Dr. Will Cole

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Click Here To Read Transcript

00:00
Speaker 1
People that were born after the year 1965, they were aging more rapidly than people born prior to 1965 at the same age. And even worse for Gen Z, we have many people in their 20s, 30s and 40s that have senior citizen cells and we see that with people that are just like dropping dead. It almost sounds fake when I say this statistic. This latest statistic is 38% of preteens are pre diabetic.

00:26
Speaker 2
What?

00:27
Speaker 1
They’re ozempic zombies. This DLP1 personality where they’re kind of decreased the cravings, but it also decreased the cravings for love and their desire for relationships. Because those same dopaminergic centers of the brain, those reward centers, are also not impacting just food, but other things in life. I’ve seen it break up marriages according to the people.

00:45
Speaker 2
Wow.

00:47
Speaker 3
Can I tell you something? The bathroom scale has probably stolen more confidence from women than almost anything else. Every morning you step on, you judge.

00:58
Speaker 2
Yourself, you feel defeated.

01:01
Speaker 3
But here’s the truth. Your scale has absolutely no idea if you gained muscle. It can’t tell if your bones got stronger.

01:08
Speaker 2
It can’t measure your metabolic health.

01:10
Speaker 3
It can’t measure your future. My new book, the Metabolism Fix, teaches you to stop chasing a smaller body and start building a stronger one. Because muscle changes everything. Pre order today@metabolismfixbook.com it’s time to stop shrinking.

01:29
Speaker 2
It’s time to start thriving.

01:36
Speaker 3
Hey, I’m J.J. virgin, Ph.D. dropout. Sorry mom. Turned four time New York Times bestselling author. As a certified Nutrition specialist, Fitness hall of Famer, and globally recognized leader in health, I’m driven to keep asking the tough questions and use my podcast to simplify the science of health into actionable strategies that help you thrive. I’d also love to hear your thoughts on the show. And here’s the fun part. When you send me your review, I’ll reply to you using my on demand virtual Me. That’s right, my team and I created a virtual JJ packed with my books, speeches and wisdom so I can personally connect with you here. Here’s how you do it. Subscribe and leave an honest review of the podcast. Take a screenshot of your review. Text it to 813-565-2627. That’s 813-565-2627.

02:34
Speaker 3
My virtual JJ will reply directly and trust me, this will make your day. So subscribe now@subscribetoJay.com and text me your review. Let’s keep thriving together.

02:50
Speaker 2
Dr. Will Cole welcome back to well.

02:53
Speaker 1
Beyond 40 thank you so much, my friend. It’s great to catch up with you.

02:56
Speaker 2
Although it’s pathetic that the way we catch up is by doing podcasts.

03:00
Speaker 1
I know, I know. I want to be a better human. I’m like, I see these people that I want to hang out with in real life, and it takes a book launch.

03:09
Speaker 2
Why we do book launches so we can hang out. Well, I am excited about this book and I want to start going deep. Actually, I want to start with your dad, because your dad died at 60. He was like, workout guy strong. Take me back to that moment when you found out.

03:29
Speaker 1
I love my dad very much and he loved me very much. But like with all family, many family dynamics, it was complicated over time and. But were. The last few years were really great. I just feel like him and I’s relationship was the best that had ever been, which is really great. The last couple of years and specifically the last time I saw him, it was so. Such an amazing, precious time. And it’s the beautiful tragedy of it all that was the last time I saw him. If I could have just had more time of that. Anyways, he was driving to pick up my mom from the airport. And we don’t really know the details of what happened, but it seems to be like piecing the pieces together from the autopsy and the police report.

04:09
Speaker 1
And what happened was he lost consciousness from some cardiovascular event, driving to pick up my mom from the airport, but he never made it to the airport. He lost consciousness, went off the road, went through the woods full speed and crashed into a tree. And the autopsy was he broke his neck from the cardiovascular event. So I know, I think it was a picture of health on the outside. Everyone would say that, right? I mean, there’d be. He was doing more than most people were for the health. So. So it really kind of took me down a cause. I was about to release my last book, Gut Feelings, and it was all book about stress and trauma. And I had to practice what I was teaching in the book.

04:48
Speaker 1
And for telehealth patients, it’s just like, let’s deal with this horrible thing for my family, but then also this stress trauma that I had to deal with too. And I was running the telehealth clinic full time, doing the podcast. The book was about to come out. It was just wild to go through that. And a storm. It was a storm, a stress trauma storm that I just, you know, that was part of the reason why I wrote this book was a learning what I had to do for myself to heal My cells what that stress and trauma that was stored in my cells. And then the studies around that Same year, actually 2023, a Stanford study came out that found 1 in 5Americans over the age of 50 had at least one organ aging more rapidly, significantly so than other organs.

05:33
Speaker 1
And for my dad specifically, if your heart cells were aging more rapidly, you were over a 200% increased risk of a heart attack, stroke, some cardiovascular event which is killing one in two Americans. And if your brain cells are aging more rapidly, you’re at an 80% increased risk of neurodegenerative. So it was definitely a tough time, but kind of implementing what I now put into book form, I now feel better than ever. But I was definitely went through a lot of flare ups because foods that I ate forever weren’t loving my body back. Like I love putting hot sauce historically had hot sauce on stuff. My gut just wasn’t handling it. And that just shows you the influence that stress and trauma can do on the gut brain axis in the vagus nerve. And your cells are you.

06:20
Speaker 1
You’re feeling on a mental emotional level feeling defensive and short and disregulated and hypervigilant. And you’re. But actually that’s happening on a cellular level. And I talk about that in the book of what’s showing up in our cells first. That’s impacting our mental emotional health.

06:37
Speaker 2
That is wild that was all happening when you were releasing gut feelings. I had no idea. So this thing happens with your dad and so it was what like two years when you figured out this whole differentiator with the. How his heart was aging so much faster than the rest of them. Like what how is that impacted you now as a practitioner, this understanding?

07:04
Speaker 1
Yeah, well, because the practicing never as far as the ortelehealth patients, it never stopped. So I was still doing that full 10 hours a day for the since 2009. So it’s like it was just I had to have margins in my life where I could. And the telehealth clinic didn’t take a back burner. But like the book and the other stuff traveling took a backseat. And it was. I’d always known the research because I see it play out in people’s lives. As far as molecular mimicry, specifically with the type of cases we see, it’s a lot of autoimmune cases, inflammation, those type of problems. But okay, we understand that from an organ system, if the immune system’s attacking the thyroid, it’s Hashimoto’s. If it’s a Brain myelin sheath, it’s Ms. If it’s the gut, it’s ulcerative colitis and Crohn’s.

07:50
Speaker 1
But then beyond sort of these overtly obvious autoimmune issues, actually that molecular mimicry, that cellular dysfunction is happening with everybody, that’s either dealing with other chronic health problems or just suboptimal health. The cellular dysfunction. Yeah. So from 2023 on, I was having to do what I recommend to telehealth patients because I was already doing all the wellness stuff. I was eating nutrient dense foods, I was exercising, but the basic stuff wasn’t cutting it. Which is where most of our telehealth patients when they’re meeting me are at. They’re pretty well read people, erudite people when it comes to health, being health efficient. So I had to go beyond the basics for me too. I had to lean into these things.

08:33
Speaker 1
Therapeutics like peptides and therapeutics like ozone, therapeutics like somatic trauma work to deal with what was going on in my body on a cellular level.

08:45
Speaker 2
Yeah, you’ve got. Now like when I look at all your books, they all have a root cause. You had ketoatarian, you know what you eat, inflammation spectrum, what’s inflaming you, intuitive fasting when you eat, gut feelings, the emotional trauma side. And so this book, why this book,.

09:05
Speaker 1
It’s bringing it all together. Actually, I never realized it until you just said it, because all the conversations that I was having in each one of those books all are in their own way, tools to reverse cellular aging, actually. So, and the science has just exploded since then. I mean, we’re talking 2017 and on. I’d been writing books. So the LAT from 2023 on, since I wrote my last book, there’s been a lot of exciting science. And really when you’re looking at accelerated cellular aging and this information, they call it the information model of aging or chronic disease. Understanding that the cells are our cel becoming confused.

09:50
Speaker 1
And more than ever before, there was a Nature study published just this past summer in June that found that people that were born after the age, after the year 1965, they were aging more rapidly than people born prior to 1965 at the same age. UK Biobank, and specifically people, millennials, people that are born in the 90s. And even worse for Gen Z, we have many people in their 20s, 30s and 40s that have senior citizen cells. And we see that with people that are just dropping for a lack of excuse my crassness, like dropping dead just he, like Here one sinking on the next and then these horribly drawn out cancer like kid people in their 30s and 40s having cancer. What’s happening? It’s because our cells are excel. Are aging too rapidly. So why this book right now is like this.

10:42
Speaker 1
I think this crescendoed conversation that I had, I guess through all my books. I didn’t realize it until you just said it. Of ways to get ourselves to remember what they are. It’s something called the. They call in the research X differentiation. Like our cells are forgetting what they’re supposed to do. And that’s why people are having suboptimal health to the brain cell kind of forgets it’s a brain cell. The heart cell forget it’s a heart cell. And that’s where chronic disease or you not feeling your best really happens. Is that the DNA, the hardware of the cell is there, the actual code of what that cell is supposed to do, but it’s being scratched or muffled or there’s this static noise. The analogy that’s used in the space is like a record player or a CD that’s scratched. The information is there.

11:27
Speaker 1
You can play it, but it’s going to skip around and be kind of the. The song’s not going to be there, the message isn’t going to fully be there. That’s what’s happening on a cellular level. There’s a cellular static that’s creating cellular confusion. And all of this conversations that I had in my previous books, we’re talking about it in more broader ways. But actually the science is saying actually this is actually messing up yourselves on a very specific way. In a very specific way. And it shows up in different ways for different people.

11:55
Speaker 2
You said something that I was like, wait, what? You said people born after 65.

12:01
Speaker 1
After. Born after 1965. Yeah.

12:04
Speaker 2
What’s that like? What’s. So I was born in 1963. So I was like going finally there’s some. But what. What. Why 1965? What’s. What is.

12:16
Speaker 1
Yeah, this is a UK Biobank study and published in Nature. And they. That was the year that they called out as seeing a specific spike.

12:28
Speaker 2
I’m going to take it because my husband’s 64 and I’m 63. So I’m totally good with the 65.

12:32
Speaker 1
Yes. You claim you get what you can get and you just like let it be and just say science said it JJ so. But the reality is it’s. Well, you know, these Gen Z people, the latest data, it almost sounds fake when I say this statistic this latest statistic is 38% of preteens are pre diabetic. What like now it’s like these kids. It used to be called adult onset diabetes. Remember that type 2 diabetes.

12:58
Speaker 2
Now it’s like no, remember fatty liver was just alcoholic. I mean come on.

13:03
Speaker 1
Now it’s like everything’s happening this rapidity, this rapid aging. And you know, for people, no matter what age you are, like if you’re teenager or you’re 50, we are all in this world of aging too rapidly. And. But the beautiful silver lining is the science is clear that this is reversible, healable, overcomeable. You could do something about it. But we cannot live the way that the world lives or we’re going to show up with the statistics that the world is showing.

13:32
Speaker 2
Yeah. And this. But if you look at a lot of the longevity work, it’s. They’re giving you a biological age and then telling you if you’re going faster or slower. But you know, from what you’re saying with all these organs in aging at different rates, the one biological age seems a bit ridiculous.

13:53
Speaker 1
Yeah, it’s a pointer. It’s an aggregation probably of overall like the, what’s the sum total of where you’re at right now? And some people have great systems and some people have stubborn areas and that’s.

14:06
Speaker 2
But you wouldn’t know which one. With one. With the one number you got no right.

14:10
Speaker 1
So no, you need to look. There’s the Stanford researchers are looking at certain proteins which they are. What I’ve heard is that they’re working on getting that diagnostics available to compare apples to apples with that data which is equaling that one in five people have one organ aging factor is like 22 million Americans over the age of 50. But that’s when you, then you look at people in their 20s, 30s and 40s, that’s a lot of people. And I can say looking at labs all day long, it’s way more than that. I mean it’s a lot of people. But you’re right, you’re not looking at one global age. But we can look today as far as like what we have access to on a clinical setting.

14:47
Speaker 1
We can look at DNA methylation and inflammation markers that kind of will not totally apples to apples look at that Stanford study. But can sort of aggregate the different organs that are maybe aging more rapidly and we can. You know I talk about that in the book too. That, that lab.

15:04
Speaker 2
Yeah. So like if it’s one in Five adults have at least one organ aging faster than the rest. What are the most like, what are the most common organs that are aging faster? I would assume, I’d assume it was.

15:18
Speaker 1
The pancreas, but yeah, I mean it’s up there. I would say more brain and heart and the immune system. When you look at cancer like that, just the immune system acceleration. But yeah, I would say brain and heart are definitely up there. And we see that statistically, right, with the amount of neurodegenerative problems and the amount of cardiometabolic issues. But you. What about muscle? Yeah, I don’t know the statistics on that, but yeah, I mean it’s, I mean it is a significant part of all of that stuff. I mean the leaner most, more tone, more lean muscle mass you have, the better all of those organs are going to be. So it’s part of that larger complex of accelerated aging, certainly.

16:00
Speaker 2
Do you think we’re going to have a test for all of this fairly soon where we’ll be able to. I mean, I guess we can look at it right now by just looking at labs and going, here are some of the different problems. Is that how you’re identifying it in your practice or what are you doing to use this?

16:13
Speaker 1
It’s multiple labs perspective from their vantage point. There are longevity tests like the, it’s the DNA, like the symphony aging cellular symphony test where you can look at DNA methylation and look at the different organs that are aging at different rates. So it’s not a complete apples to apples with the Stanford study. And that’s why I’m saying based on DNA methylation and inflammation and cardio metabolic markers, I could tell you it’s way more than one in five per people. And it’s slightly skewed because I’m not talking to the average population. I’m looking to people talking to people that actually have things to optimize. But still, it doesn’t take a rocket scientist. Just takes some good old fashioned common sense to look around at the world around you and say, yeah, it’s just because something’s common doesn’t make it normal.

16:59
Speaker 1
These chronic health issues are just suboptimal. Health is not normal. And that’s showing up in different ways from autoimmune conditions, cancer, heart disease too, the fertility rate, I mean the total fertility rate. We are below the total fertility rate right now in the United States, meaning we can’t even sustain our population. And that’s why it’s because the reproductive system is aging more rapidly. We’ve seen a 50% drop in sperm count in the last 50 years. What? Like people should really wake up to this. This is unsustainable for the human race.

17:34
Speaker 2
Okay, so why do you think all of this is going in this direction?

17:39
Speaker 1
It’s. We really uncover a lot of things in the book that I would say if we’re to go down the main ones that I think it’s the foods we’re eating and the foods we’re not eating. Obviously it is not just what we’re eating, but it’s when we’re eating. A lot of the researchers call it the chronobiological disorder. It’s like we’re just never giving our body a reprieve, which you and I have talked about in the past. There was this relationship with fasting windows to allow these pathways to these cellular renewal pathways like autophagy and mitophagy to actually do what they’re supposed to do. I think it’s our relationship to light because food kind of tells our body cells how to function and light tells our central part of our brain. And then that’s connection with our cellular clocks how to function.

18:31
Speaker 1
And we are inside away from the sunlight and then around these, this art blue light all day long and then into the night. I scrolling on our phones that’s really messing up our cellular clocks and they’re tick tocking too fast and that’s accelerating aging are the dirty light in our life. I think man made environmental toxins is another one. It’s herbicides, pesticides, microplastics, forever chemicals, heavy metals, that’s a big part of it. Our great grandparents didn’t have to deal with that. It’s environmental toxins, like biotoxins, like nature toxins that are just exacerbated because of the man made toxins like mold, mainly mold toxins, mycotoxins, but bacteria and viruses. But I think we’re looking at labs all day long that it’s really the EMF component from electronics that’s aggravating mycotoxins, mold toxins, making mold toxins more aggravated. It’s for lack of better word, pissing off.

19:29
Speaker 1
The EMFs from our electronics are pissing off mold toxins in our homes and offices which is also impacting our cell, making our cells more per to absorb more of these mycotoxins. And then the last piece I would say is the mental, emotional, spiritual stuff. It’s chronic stress, unresolved trauma and spiritual disconnection. I think our individual and societal relationship with God or lack Thereof is the last piece. So we have to look at this larger cellular mismatch that all the things I just said. That’s what’s causing cellular confusion. Our cell do not, does not know which way is up. It doesn’t know what it’s supposed to do. It’s losing recognition of self. But think of. That’s how the researchers refer to molecular mimicry when. It’s when the immune system’s attacking parts of the body with inflammation. But think about that. What’s happening.

20:18
Speaker 1
That’s how people show up to the world when they’re dysregulated, They’ve lost recognition of self. They’re hyper defensive, they’re dysregulated, they’re kind of toxic. We love them, but we all could be kind of toxic. That’s actually what’s happening on a cellular level. So it’s like the hermetic phrase, as above, so below, as within. So without. It’s all happening there on a cellular level.

20:41
Speaker 2
That sounds pretty bleak. We’re going to unpack one by one.

20:45
Speaker 1
And God bless you and see you later. We’ll just land it right.

20:49
Speaker 2
Like, wow. All right. We’re not going to leave it there because that would be ending on a low point. But like someone listening right now going, okay, I’m hearing all this, which you look at just, you know, I think of what life was like growing up and what it’s like now. And it’s. The dramatic shift is so insane. Right. You know, and I thought things were bad because my mom gave me Pop Tarts.

21:12
Speaker 1
Yeah. Oh, my Lord. Yeah.

21:14
Speaker 2
We had home cooked meals. Right. We had home cooked meals for everything and some Pop tarts. And now 70% of what people eat are things like Pop Tarts. So. Yeah.

21:22
Speaker 1
Yeah.

21:22
Speaker 2
You know, so here we are now. And the people listening, the woman listening is really, she’s smart. She listens, she reads, she’s doing all the things. But she wants to know right now, listening to this because she’s still bombarded by toxins and she’s still out in the world. So she’s going to be eating some of the foods that maybe aren’t the best. What are some of the things she could do? Like what would be the tests or what she could do initially to find out where she stands, Especially since some of these, you know, you can’t get aging organ tests yet. But, like, what could she do as the basics to go. Here I am now to get a baseline.

22:03
Speaker 1
Yeah. And again, with our telehealth patients, we can look at organ aging. Again, not the same marker as the Stanford studies, but we can look at DNA methylation in the body and different markers that are corresponded with certain organs. So it’s.

22:20
Speaker 2
And one question there, with the DNA methylation, if someone’s then a poor methylator, are they going to age faster if they didn’t correct for that?

22:31
Speaker 1
Yeah. And we have to look at that interplay between genetics and epigenetics. Right? We know some people have a harder time than others with certain gene variants, but genes, as the analogy goes, genetics loads the gun, epigenetics pulls the trigger. So we understand genetics, it’s a piece of the puzzle, but it’s not the totality of how long or how well somebody lives. So, yeah, for somebody, you’re right, those are sobering statistics. But the amazing, beautiful blessing, the silver lining in this mad world that we live in is that we actually know more than ever before. So it’s like, yeah, we don’t have to be a statistic. We can do the best we can and we’re going to see amazing results. And guess what?

23:08
Speaker 1
Things don’t have to be perfect for you to thrive and for you to live the life you were created to live. You just have to do the best you can and give the rest to God. And it’s like the humanity, all the things that I just mentioned that are like these sobering statistics, it really can be boiled down to this. When mankind pretends to be God, there’s unintended consequences and sometimes intended consequences. So really it’s not that complex. Just live more in alignment with nature, live more in alignment with how God created us. That’s the basic message here. And then we can use amazing advancements in science to do it in a modern way. Right? And then there’s some good ancestral wisdom that we can implement too, like both and not either or here.

23:52
Speaker 1
So it really, I mean, depends on where you want to start. But I would say lean in to these practices of health. But if you want to start with diagnostics, with some basic tests, I think anybody could get to see where they’re at. I think understanding someone’s metabolic health, obviously is a good start to see because it’s the. Probably one of the biggest gasolines on the cellular aging fire is if you look at like some statistics, not upwards of 93% of the United States is metabolic and healthy. So if you’re looking for like, hey, where do I start? I would want to see where’s your glucose? And A1C glucose under 90 fasting blood sugar A1C under 5.5. Triglycerides, we want under 100 HDL or good cholesterol. We want to be above 59.

24:41
Speaker 1
Inflammation markers like high sensitivity C reactive protein under 1, homocysteine and inflammation marker under 7. That if you are in the op, if you’re not in the optimal zone there, that’s a good sign that hey, we have some work to do. But your cells are aging more rapidly. And then from there you can look at more granular data on like looking at your liver markers or your brain markers, your gut markers or your hormonal markers. Though it depends on what that person’s health history in labs we need to run. But I think understanding your metabolic health is a good starting point for most people.

25:17
Speaker 2
Honestly, if most people knew that could I always look at go. If you knew these things and then you did the basics to improve that, a whole lot of stuff that you would go down the rabbit hole on, you don’t even have to look at. Now I know in the book you really lead with food. So let’s say we’ve got someone listening and they go, but I eat healthy, I eat clean. What, what could she potentially be missing? And I always like to add before I take away. And I think we don’t focus enough on that. Right. It’s always focused on the macros or the cat. Like what could she be missing that would really be impactful here for her.

25:50
Speaker 1
Cellular health one is, let’s just talk about macronutrients for a moment. And I most of your listeners, because they’re taught by you, they know more than most people. So I don’t want to belabor things that they know already. But health, I’ll just call this out when it comes to healthy cell membranes, because every cell of your body, we have 30 trillion cells are encased, protected, embalmed, Embalm is a bad word. They are surrounded, they’re protected by this cell. Embalmed. That’s horrible. Anyway, you know, you all know what I mean. They are, they are protected by this cell membrane, which is a phospholipid healthy fat membrane. And they, we need a perfect amount of permeability and structure of the cell membrane. We need it to be malleable enough, permeable enough to get nutrients in, but rigid enough to have structure.

26:44
Speaker 1
The problem is most people have oxidized, inflamed, sort of rusted BB bullet, if you will, cell membranes. And we need healthy fats to start to replace that. So healthy saturated fats Healthy monounsaturated fats, long chain omega fats. We need to be focusing on healthy fats. Now for some people that can look like more of a ketogenic type, 60 plus percent healthy fats. For some people it’s just moderate fats. You need to find your fat sweet spot that you can handle digestively that is diverse. That’s not overly doing. One type that’s eclectic from a saturated monounsaturated polyunsaturated omega. That’s going to beautiful for your cell membranes. Like I’ll call out one is C15. It’s in things like D fats, cheeses. Right. It’s a saturated fat. That’s it’s estimated like one in three people can have what researchers call cellular fragility syndrome.

27:41
Speaker 1
And you we can measure this on telehealth patient labs. And that is roughly how many people have it that I find clinically your cells more fragile. That membrane is too fragile. You need it to be malleable and strong instead of this brittle ossified cell membrane. Because what’s on the cell membrane it’s receptor sites for hormones and neurotransmitters. So if your hormones are off or your neurotransmitters are off, is it a hormone or neurotransmitter problem or is it a hormone or a transmitter neurotransmitter signaling issue which is happening on the cell membrane. So look at fats and then if you look at like other like micronutrients or let’s just say plant compounds, I would look at something called xenohormesis, which hormesis, which most of your listeners will know are things like fasting ketogenic diet.

28:31
Speaker 1
Those are hormetic effects or the dose makes the poison while the dose makes the medicine. If you can kind of get your researchers call it adversity mimetics, things that mimic adversity for your body. Actually cell it’s like a cellular boot camp for your cells to become stronger, upregulate these autophagy cellular recycling and mitophagy mitochondrial recycling renewal pathways. Well plants do that too. So fasting ketogenic diet which is fasting mimicking cold plunge sauna therapy. What else was going to say? High intensity interval training. Anything that’s slightly stressful, that is cellular recycling. But specific food compounds are these xenohormetic compounds. Plants that went through stress, they pass that intelligence onto ourselves. So the cells of that plant then tell ourselves you’ve got this. Remember you’re a brain cell. Do What God created you to do or whatever cell you’re talking about. So it’s renewing that cell.

29:34
Speaker 1
Nature’s beautiful that way. So think of it like these brightly colored berries, like wild blackberries or blueberries, those flavonoids, those polyphenols are what the plant made to become more defensive. So organic produce that doesn’t live in like a perfectly sterilized sprayed environment, it has bugs, it has sunlight, it has harsh conditions that makes the plant more resilient like God wanted it to be. That bitter. Poly extra virgin olive oil have these polyphenols that the plant makes these to become more resilient. And then the plant helps ourselves become more resilient. So think herbs, spices, brightly colored fruits and vegetables, pomegranates, blackberries, blueberries and tea. How could I say I’m drinking tea right now? So like a oolong tea, Pu erh tea, that bitter tea. Embrace the bitter. We don’t like the bitter in our culture.

30:31
Speaker 1
But like bitter greens, like those things are xenohormetic tools to teach ourselves to become more resilient.

30:39
Speaker 2
I think this is an important point because there’s like a whole school of thought out there. There’s like, avoid those things. They’re nature’s toxins. It’s like, no. So you know, no.

30:50
Speaker 1
And look, the sweet spot isn’t that funny, right? Because people you and I know, I mean, look, if someone has digestive problems, you don’t want to be go flaring your gut up, but you have to meet your gut where it’s at. But believe me, if it’s not the tea or it’s not whatever plant food you’re talking about that’s the problem. It’s your lack of resilience in your gut because of what modern world has done to our the human microbiome and gastrointestinal health. So yeah, meet your gut where it’s at, you build, heal your gut and build resilience. But the goal is to reintroduce foods and not just live on five foods.

31:25
Speaker 1
Because I think people to your point, I think it’s a great call out people that unnecessarily restrict foods because of plant anti nutrients or things like lectins and phytic acid and oxalates and these type of things that some people do need to limit or remove for a time while they heal their gut. But to say that’s forever and ever amen and you do it forever or everyone should do it because you fear the plant entry plant anti nutrients, what it’s done is created. Such a lack of resilience in people because of this, they’re not having any xenohomesis. So then they eat anything and things that they never had a problem with, they have reactions to. So you have to build resilience and teach your. Your body gets taught from the plant.

32:07
Speaker 3
Foods, even when you’re doing all the right things. Your strength training, staying active, prioritizing protein, keeping the muscle you built over a lifetime gets harder with age. Now our parents were told to accept.

32:19
Speaker 2
That it’s just getting older.

32:21
Speaker 3
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32:58
Speaker 2
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33:00
Speaker 3
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33:12
Speaker 2
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33:14
Speaker 3
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34:10
Speaker 3
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35:14
Speaker 2
Love that you’re bringing up the word resilience. It’s funny, when I wrote the Virgin diet, it was never drop seven foods forever. It was an elimination diet. It was like people would come up to me years later and go, I’m on your program. I go, it’s a three week program. It was, the whole point was to take it out to see how your gut responded, to see if we needed to heal your gut. And that’s what I’m hearing here too. And I feel when you talk about living as nature intended and then doing things like heat and cold, so much of what we have to do now is to put back in like, you know, a gym’s a great example. Could you imagine a thousand years ago they would look at us and go, what on earth are you people doing?

35:55
Speaker 2
You know, because that was just normal life. They did not have to create a gym to mimic. Like if you looked at a lot of the old gym equipment, it mimicked old farming equipment.

36:06
Speaker 1
Yeah. Functional movements. Yeah, it’s so true. Right. We need like to be carve out specific machines. Specific everything.

36:15
Speaker 2
Treadmill. Oh my gosh.

36:17
Speaker 1
Yeah. Just called walking uphill something heavy.

36:22
Speaker 2
What have we done here? Yeah, so I would love to address that because you brought up the when you eat, I think timing and light is such a huge piece that we miss. But I do want to address the fasting piece because, you know, I talk a lot about muscle and I feel like there’s lot of misunderstanding between the fact that we both need to build up and break down, that there must be a balance here, that you need to do both. When is aggressive fasting though, something that would be good? You did write the book on fasting. When is it not good? When do you need to be cautious? Like, where does that fit into the whole cellular healing?

37:01
Speaker 1
It’s, it’s another hormetic tool it’s another adversity, mimetic and something that’s mimicking cells, like a cell rehab, cell gym. And it teaches our cell to become more resilient. So, right. What’s happening now is this ancient promote when. When people are going through chronic health issues or just you not thriving. If anybody is watching this or listening to this and just not feeling their best, why that is. No matter where it’s at on a cellular level, there’s some semblance somewhere on the cellular dysfunction spectrum. There’s the cell danger response that’s happening, some in subtle ways, some in more extreme ways, and everything in between.

37:40
Speaker 2
Explain the cell danger response.

37:42
Speaker 1
Yeah.

37:42
Speaker 2
So to a fifth grader.

37:44
Speaker 1
Yeah. So it’s a defense mechanism that your cell becomes trying to protect you. I mean, it’s meant there to protect you, but it cannot distinguish between physiological and psychological threats. Meaning that something physical, like a food that doesn’t love you back, an environmental toxin, a mold toxin, or stress and trauma. What happens is the cell membrane that we talked about earlier, that becomes more rigid, becomes more ossified, oxidized, it becomes more rigid, becomes more inflamed. And those little mitochondria that are meant to have their own DNA, I mean, they’re basically descendants of bacteria, which is beautiful to think about that. And they have this beautiful communication line with our microbiome bacteria. So we have to. The microbiome mitochondria crosstalk this. Our cells are talking to our gut bacteria through the mitochondria mainly and the cell membrane.

38:36
Speaker 1
And you know how people can get leaky gut syndrome or leaky brain syndrome, or we can have leaky mitochondria syndrome, and the mitochondria become leaky and start leaking out these reactive oxygen species, which is sort of a byproduct of energy, sort of a kind of like a dirty fuel when the. When the body’s stressed. And there’s this pathway, we’re bringing it to fasting real fast, is that there’s this pathway called MTOR that is high for too long, too high for too long for too many people. So mtor, we need it. God made it. It’s meant to build muscle. You and I talked about this last time, actually. I think were on this mammalian or mechanistic target of rapamycin that we need for healthy muscle, but it’s just too high for too many people because we’re eating too many foods too much.

39:26
Speaker 1
And all of this other modernity stuff that I talked about earlier, it’s throwing off this pathway called MTOR and this AMPK pathway, which is kind of the CFO of the cell, it’s telling the body, hey, we’re good because all the food’s here. We need to handle this is like production time because it’s. The body just is in this mode because we’re constantly feeding it foods that don’t love us back too often and then all the other type of things. So it’s like it’s hijacking the cell in many ways. It’s confusing the cell. So MTOR is high and autophagy is low. The cellular recycling pathway. So fasting helps to reshift. All of that. It’s saying, hey, look here, you need to focus on actually renewing yourself cell instead of growing and growing, dysfunctionally growing and producing these inflammatory cytokines.

40:15
Speaker 1
So to answer your question, I guess is a long way of saying, how much medicine do your cells need? And some people need a lot of cellular medicine. Some people need less of it. So the dose makes the medicine. And Paracelsus, he was the father of toxicology, and he’s known as the Martin Luther of medicine in Switzerland in their late 1400s, early 1500s, he called fasting the physician within, which I think is a beautiful way of putting it. Some people need a lot of physicians, cellular physicians. Some people need less. So it’s so reductive to say women can’t fast or who are we talking about? What type of. What is she going through and how is she fasting? That context, that bio individuality matters. So it could be as simple as a 1212. Just don’t eat so late at night.

41:05
Speaker 1
So your body’s fasting through the night.

41:07
Speaker 2
That should be a foundational statement.

41:09
Speaker 1
Like. Right.

41:10
Speaker 2
That should just be a rule.

41:12
Speaker 1
Yeah, exactly. But many people aren’t. Right? So that if nothing else, if you’re like, no, I don’t feel so good with like deeper fast, okay, Meet your body where it’s at. Maybe that is too extreme. But at 12:12, like you said, the fasting type A aficionados won’t even call that fasting, but it is. You’re fasting through the night until you break fast at breakfast in the morning. And that’s where there’s autophagy. The cellular renewal pathways are happening through the night when you’re sleeping, but you need proper sleep, REM and deep sleep. You’re eating too late at night. Your body’s focusing on digesting food and not on cellular repair mechanisms. And then from there you can dig into deeper fast. Anywhere between a 168 and 18, 6. That’s a fasting eating window to multiple day fasts.

41:56
Speaker 1
With proper hydration, electrolytes and supervision when needed can be an amazing healing time for people who need that amount of cellular medicine.

42:07
Speaker 2
I look at all of these things and they’re, I think the important thing. You brought up this idea of xenohormesis and creating stress so your body gets more resilient. I feel like we’ve lost this whole idea of resilience and that we have to do both breaking down and building up. And the real thing is finding the balance between them and using these tools to get to that point. It’s one of the things in the book you have Beyond Biohacking and you’ve talked about getting back into nature, but then we’re in this industry, you know, where you go to the conferences and there’s people like, I walked into Dave’s Beyond Biohacking last couple months ago and literally there’s a girl sitting in a sound bowl with her eyes closed as everyone’s videotaping her.

42:54
Speaker 2
There’s another one in some kind of weird spinny thing, you know, with lights flashing. And I’m like, I have literally entered the twilight zone here.

43:03
Speaker 1
So meanwhile, it’s just like, take your shoes off and get in the grass.

43:06
Speaker 2
Yeah, exactly. I go outside with the dogs and get in the grass. And so where’s the hierarchy here? Like what are the things we.

43:14
Speaker 3
Can get from nature?

43:14
Speaker 2
What are things that maybe we could get a little bit more help with and grab some of these tools? What, where do we go?

43:21
Speaker 1
The way that I put that chapter is we showed it the biohack, therapeutic that has its place. Right. Some for certain people and certain cases and. But a lot of them at the end of the day are mimicking nature. Right? I mean, red light therapy, sauna, cold puns. Like you said, our ancestors would just call that life.

43:42
Speaker 2
Yeah.

43:43
Speaker 1
I mean, they would just get outside and get in nature. So is it efficacious doses of certain things? Is it like, especially if you’re inside more. Can you concentrate and mimic nature in many ways with Biohack therapeutics? Absolutely. But it doesn’t. It should not replace nature. It’s convenience. Right. People pay for convenience with our modern life. And that is the blessing of the time that we live in where we. If you have access to it, you can utilize it and it could be fun and restorative, but to me it’s best used. These biohacks are best used when they are used, when it’s in addition to just some practical nature stuff. So throughout that chapter and other chapters I showed what are ways that are just connecting to God’s nature. Like, like PEMF’s a good example.

44:34
Speaker 1
Like grounding therapy around grounding, the research around grounding and what that does to our cellular electrical system and how there’s like nature made non polarized God made EMF from our planet, from the earth, from grounding in the research out of Japan and South Korea of Shinrin Yoku forest bathing. Well, okay, you could go and spend some time in nature, take your shoes off and just do some grounding. Or you can go buy a PEMF grounding mat that has also amazing data around that. So is it one better than the other? It just depends on how you’re going to use it. Are you going to go do the grounding? And then of course there’s certain frequency that they can do with technology that has some place. But it’s not a replacement of nature, it’s just kind of mimicking. A lot of this stuff’s mimicking nature.

45:21
Speaker 1
Same with light therapy. Same with the cold plunge. Look, at the end of the day, this is the truth. Same with peptides. Like peptides, your body’s indigenously making this stuff already. So. But, and does taking exogenous peptides have a therapeutic benefit? Of course. But if you improve your metabolic health and gut health, your body, your. You have a peptide pharmacy in your gut to make GLP1 and to make BPC 157. So start with the basics to get your body to do it on its own or connect to nature, which we’re intimately connected and then from there use the blessings of modernity with some biohacks.

45:59
Speaker 2
Yeah, well you can’t roll the peptides out and just leave it at there. It’s the hottest conversation going and you did do an entire chapter on it. And the reality is most people do not have great gut function right now. So they’re probably not making their own pharmacy too. Well, of course we want everyone doing the found things. And I see two roles here. One helping you heal and two, maybe optimizing. So what’s your, give me a little course on peptides here.

46:29
Speaker 1
The signaling molecules. They’re cellular signaling molecules, which is obviously that’s why they’re in the book, because they teach our cells to do. They’re another way to decrease that X differentiation. In my mind, if you look at the mechanism of action of how they actually work. Same with stem cells you know, stem cells in many ways, how they, the mechanisms are actually pretty exciting when you look at how they have these sort of tunneling microtubules and stem cells actually donate mitochondria, it’s their own mitochondria into our cells. I mean what’s happening on a cellular level with stem cells and peptides is pretty profound on a cellular level. So peptides specifically.

47:08
Speaker 1
I agree with you that people have such messed up gut health that pragmatically, even if you get somebody and this isn’t everybody, but if you get a lot of people to the place of really good gut health, they’ve done a lot to work on lifestyle. Maybe they saw someone in functional medicine to improve their gut health. They still won’t necessarily. Everyone won’t be 100% because of modernity, because of years of being suboptimal and struggling and what we’ve done to the human microbiome in the connection to the soil microbiome really in our planet. So I’m a pragmatist with this, that I think that pragmatically a both and not either or approach deal with these foundational things and then guess what? You don’t need that many peptides and you don’t need to be on them for long for most people.

47:54
Speaker 1
So I would say microdose cyclical with pure peptides. That and a case specific basis is a smart way to do it. And that’s how I see it helping people. I’m a fan of them. But it’s the way that America does it. It’s. I think it’s not having that nuanced conversation. It’s like if the American cliched way is if a little is good, the more is better and people are macro dosing these GLP1 agonists in perpetuity and creating anecdotally I would say people telling me they’re OIC zombies. Their GLP1 this GLP1 personality where they’re kind of, yeah, decreased the food noise, decreased the cravings, but it also decreased the cravings for love and their desire for relationships. Because the same dopaminergic centers of the brain as reward centers are also not impacting just food but other things in life.

48:45
Speaker 1
So there’s some of this dulled relationship problem with even their I’ve seen it break up marriages according to the people.

48:52
Speaker 2
Wow.

48:52
Speaker 1
Which is kind of radical to think. I think more research needs to be done on that phenomenon. Probably multifaceted. But it is a phenomenon that I keep hearing from People, when you hear it enough times from people, they’re like, yeah, it’s just, yeah, I got skinny. But like it wrecked my marriage or like I just lost all desire. Now you could say. The flip side of it is that maybe it just. When people lose weight, they get more confident and they just cracks in the relationship. Just they. The things they put up before, they’re not putting up with now. Maybe there’s some of that, but I do think there’s a. Some neurochemistry issue that we’re overdoing a good thing. And the truth is somewhere in the middle. And we like to overdo things.

49:31
Speaker 2
Well, you look at even how that the pharmaceutical delivery of that drug is the problem to begin with. Like, if you think about that one, it would only make sense to dose it right up to the point where you put a little bit of a down dial on food noise. Like you’d never want to shut it off. And that’s the problem. I’m like looking at this going, this is dumb. This is.

49:55
Speaker 1
You’re absolutely. I think you’re absolutely right. Like, people need to realize that sweet spot is where we’re losing the magic of these peptides. That’s specifically the GOP ones is because that food noise isn’t pathological. I mean, it’s.

50:08
Speaker 2
We.

50:08
Speaker 1
We’re supposed to have hunger signaling. So just shutting it down. And then what I’m seeing, jj, is that it’s done the wrong way. The way that the country’s doing it and the world’s doing it. It’s creating eating disorders because then they feel any hunger and they’re afraid. They’re like, no. Up the dosage because they’re just afraid. That’s not normal. I mean, we just need to take the edge off of it sometimes because of this larger gut brain dysregulation. I think that’s where you can see some good result and then come. Come off of it when you can.

50:38
Speaker 2
Yeah. Roll it down. I mean, but you look. Yeah. And now we’ve got like the skeleton celebrities.

50:45
Speaker 1
Yeah. They’re over and. And again that’s. They’re in the public eye. It’s just like. I can’t imagine that. It’s just like you’re thinner is better. And yeah, I don’t want to digress, but remember during COVID everything was like body positivity. There’s no such thing as a bad food. Then as soon as GLP1 came out. Nobody’s talking about that.

51:02
Speaker 2
That, that went right out the Window.

51:05
Speaker 1
It’s like yeah, they really meant it. They really meant it.

51:08
Speaker 2
Yeah, exactly. Any other peptides that you are a big fan of here?

51:14
Speaker 1
Yeah, I mean we go into detail in the book but I Some of the ones that I’ve used personally after like talk about post what happened to my dad and like this sort of gut inflammation flare up it game changer for me again cyclical. Don’t always have to be on them. I’m not on them now but the sort of the glow close stack as some people call it. But a BPC 157 KB KPV TB500 copper peptides cyclically with those. And I’ve listened to a lot of peptide researchers, they tend to. I did them mostly combined but I’m also experimenting. I have experimented in the past taking them separately. I didn’t personally notice a difference one way or the other like the compounded together versus the singular.

51:58
Speaker 1
But a lot of the peptide researchers tend to recommend them having separately as far as the research is concerned from a stability shelf life standpoint. So there’s. Those have been a big one for me. Celan Cemax. I’ve seen great clinically for telehealth patients. I personally haven’t used that from a neuroplasticity brain health mood standpoint. Epitalin, I like the research around it’s improving RAM and deep sleep and it’s potential telomere lengthening these end caps of our chromosome from a cellular aging standpoint. And I’m probably missing some but. Yeah, but those are. I would say those are the main ones that I’ve used in my healing journey.

52:41
Speaker 2
I know there’s a lot of talk out there with GHK Copper. Do you think we’re going to have some issues with people getting a little zinc deficiency out of balance with that?

52:51
Speaker 1
I think it could be, yeah. I think to the same point that were talking about earlier. It’s like too much of a good thing. And these.

52:58
Speaker 2
Yeah, because you never hear that part and I’m like oh, you know.

53:02
Speaker 1
Yeah. How long? How much are you taking? How much? How long? Yeah, for sure.

53:05
Speaker 2
Yeah.

53:06
Speaker 1
And yeah, it’s just we cannot macro pulse the pathway and not have unintended consequences.

53:16
Speaker 2
Say that again for the people in the back because boy, that one.

53:20
Speaker 1
Yeah. Like pharmaceuticals have side effects because you’re like shutting down a pathway and you’re like nothing could go wrong here. It’s like. Well yeah. And the same thing can happen with peptides. You’re modulating your biochemistry so you have to Be mindful of the ripple effect, the cascade that I could bring long term, if you continue something long term.

53:41
Speaker 2
All right, so you have your book, Heal your cells. Where, like, best place for people to get that. I’m assuming grab it over on Amazon. And where can they find you? Give me all the goods.

53:55
Speaker 1
Thank you so much, friend. I appreciate it. So everything’s at drwillcole.com-r w I l l c o l e dot com and yeah, just go to Books, heal yourselves. It’s on Amazon, Barnes and Noble, independent bookstores. I have a podcast called the Art of Being well, which you’ve been on and you’re going to come back on, which I’m so excited for your book. So excited for it. Yeah. Yeah. Hey, it’s time. Time is God’s timing. Is the timing. But yeah, it’s all the things are drwillcole.com I’m @drwillcole on social media.

54:30
Speaker 3
All right, we’ve got the speed round ready.

54:33
Speaker 1
Okay. I’m nervous.

54:35
Speaker 2
Overrated longevity test.

54:40
Speaker 1
I don’t know, actually. I, I, someone asked me that the other day. I don’t know. I’m not paying attention to the ones on social media to say it’s overrated. We just run what we run. I don’t have a good answer there, but I’m sure there’s lots of overrated ones because people love to overstate things on social media.

54:59
Speaker 2
Well, I think a lot of these biological age tests are just ridiculous. Like someone’s like, I’m 20. I’m like, you’re not 20.

55:05
Speaker 1
Yeah.

55:05
Speaker 2
Yeah.

55:07
Speaker 1
Okay, so we’re, I, you’re 45, Betty. Yeah, yeah, I hear, you know.

55:16
Speaker 2
Right. Maybe not. Those ones get me crazy.

55:19
Speaker 1
Jennifer. Not 20.

55:21
Speaker 2
Most underrated longevity test.

55:24
Speaker 1
Underrated. I would say there’s metabolic test that I would say, like the basic ones that anybody could get from any doctor. Those glucose, A1C CMP, looking your liver enzymes, your inflammation markers. Like, go back and listen to that. If people got that, that’s a good, I would say a surrogate marker set of markers that could show you more or less where you’re at on that cellular aging spectrum.

55:54
Speaker 2
And most overrated supplement for cellular health.

56:03
Speaker 1
I think, look, I think there’s a lot of great brands out there, right? But sometimes it’s not that it’s bad or overrated per se. You’re just paying for the branding. So if that’s okay. And some people want that, right? That’s like they want that sort of designer handbag of supplements. Then that’s cool like there. But just know that you’re paying probably a bit of a markup up for that prestige of the brand. So I think sometimes look you. There’s a. That’s not always true. Sometimes ingredients are just expensive and you’re just paying for the expensive ingredient because it’s supply, demand, economics. But I think sometimes just that. Become label literate. Become label literate. Know what you want from an ingredient active ingredient standpoint.

56:50
Speaker 1
Support brands that are transparent and then decide the price point that you want and the specific brand that has the transparency and the. Decide for yourself. I don’t know one specifically overrated longevity space, but I’m sure there are. I’m sure there are ones.

57:06
Speaker 2
It seems like there’s one. A new one every week that is.

57:09
Speaker 1
Yeah.

57:10
Speaker 2
What about the most underrated.

57:14
Speaker 1
Supplement? Underrated longevity supplement. I will say this is that one is answer or not. But I would say organ meat supplements are underrated because you a may not think of them as longevity and people aren’t eating enough of them. I would prefer you to get them from your food. Right. But problematically getting some of these minerals. Yeah, but no, people aren’t going to do it, but. So I think it’s not the same as food. But it’s like the next best thing that I think they’re. You don’t think of them as longevity, but they’re actually really needed for longevity. They’re the raw materials for a lot of cellular health. You think of. Of vitamin A and iron and B vitamins and copper and zinc, all these amazing compounds. You need it from a cellular health standpoint. So I would say maybe those.

58:04
Speaker 2
I’ll never forget. I was in London in my teens and I thought I was having a piece of steak out of steak and kidney pie and they teased me and gave me kidney. First and last time ever eating an organ meat. It was like the most icky. Yuck. But I do use pluck organ meat seasoning. That’s what I use.

58:23
Speaker 1
Oh, I don’t know about that one. So is it.

58:26
Speaker 2
You don’t know about pluck?

58:27
Speaker 1
No,.

58:30
Speaker 2
It’s fantastic. It sounds disgusting, but it’s organ meat seasoning. It’s fantastic. We put it on chicken thighs. It’s like it’s absolutely fantastic.

58:39
Speaker 1
There you go. That’s another way to do it, right. It’s just the same concept, right?

58:42
Speaker 2
Yeah. So like it’s just. You have to get over the idea of it, but then the taste is right. Terrific. Because it’s the texture of the organ meat I do not like.

58:50
Speaker 1
Yeah. Another way to do it is like the ancestral blends, like Force of Nature has, like, they’ll mask it. It’s like 2/3 regular meat, one third organ meat, which you could do that on your own. Or brands like Force of Nature does that as well, which. That’s how I do it. I don’t have straight up liver.

59:06
Speaker 2
That’s what we give to the doggies. The doggies get that from. From. Maybe I’ll just sneak their food. They wouldn’t like that, though.

59:16
Speaker 1
Yeah, just share. Share the bowl with them.

59:19
Speaker 2
Yeah, that’s great. One thing that you changed about your own routine after writing this book.

59:27
Speaker 1
Huh? I would say I’m more diligent with my relationship to light. So getting morning light and then wearing blue light block glasses. Blue light blocking glasses more diligently. I’ve worn them for years, but more diligently in the evening and improving my sleep hygiene, because that’s one of those things that can throw off that. That make your cell kind of lose track of time and age too quickly. So I would say clean up, decrease my exposure to dirty man made light.

59:58
Speaker 2
That’s a good one. The wellness trend you’re quietly done with.

01:00:05
Speaker 1
Okay, so here’s my. This is a hot take. And I wonder if how you feel. I am. Trends will come and go. Sometimes trends are great because they raise awareness, but all the protein conversations, I’m. I’m kind of tired of it. I think we needed to have it as a culture because people weren’t optimized. But I do think it’s like when you. Then. Now you’re like, protein Pop tarts. Protein cold.

01:00:30
Speaker 2
I was just gonna say, now there’s protein. Everything. Here’s the. Here’s the good news. I was thinking about it. Go. You know, when you look at every single diet trend out there, they manipulate carbs or fat. Carbs are fat. Carbs are fat. No one ever talks about protein. So it needed its. It needed its own PR campaign. And like anything else, we then took it way too far. I think probably because there was a study that came out that showed, like, if you ate protein with ultra processed food, it wasn’t as bad for you. And I’m like, oh, no. You know, it’s just like when the study came out that said if you take vitamins, when you eat McDonald’s, you lower the inflammatory response. I go, these are bad. Bad study to do so. You know, but great.

01:01:09
Speaker 1
Great for big food, though.

01:01:10
Speaker 2
Great. I mean, when I, you know, when I wrote the Virgin Diet I remember it was like all of a sudden I was virgin diet and wheat belly and grain brain and all of a sudden gluten free junk food became like, and now we’ve got protein. High protein junk food. Yeah, just, you know, ice cream is ice cream. Cookies are cookies, Pop tarts are pop tarts. Eat real food.

01:01:32
Speaker 1
Yeah, yeah. Have it if you want to, but it’s like to pretend it’s like, oh, it’s I’m getting my protein in from this pop tart, is not it?

01:01:40
Speaker 2
Yeah, don’t kid yourself. Just go eat some fish, it’s fine. All right, last question. Closing tradition. Imagine you’re sitting across from the woman listening today who is overwhelmed, confused and worried about her future. What’s one thing you’d want her to hear before she turns this episode off?

01:02:00
Speaker 1
That your body is amazingly resilient and you were created for great things and you do not have to have it all figured out to start leaning in the positive direction. And I think just start leaning into the things we talked about today, things I talk about in the book. Your body’s amazingly resilient. I see people that do microhabits of things that love their body back and it makes all the world of the difference. So I think sometimes we can get paralysis of analysis and think, okay, if I have to have it all figured out to do anything that’s a lie from the devil, just do a little bit each day, meet yourself where you’re at and then guess what? The things that overwhelmed you today aren’t going to overwhelm you in a few months. So just start off slow, lean into it.

01:02:46
Speaker 1
Lean into the things that love you back. You all know the things that love you back. And if you don’t know, just listen to some of the things we talked about today and then you’re going to start getting intuition and discernment. You’ll start to hear that still small voice that tells you, yeah, this is the right path and don’t get disillusioned from all the noise on social media. And even if it’s me, even if it’s jj, you follow yourself of knowing what loves your body back. You can listen and learn from people, but the end of the day, you’re your own end of one experiment. Find your own bio individuality. So that would be my words of thoughts for everybody today.

01:03:22
Speaker 2
Fantastic. I’m going to put all of this@jjvirgin.com forward/ Heal yourselves because I’ve already used your name a couple times. I’ll put our past interviews too Links to all your social website. Everything else link to Grab that book and congratulations on your book.

01:03:40
Speaker 1
Thanks jj. Thank you for the years of support and I really it does not go unnoticed. So thank you.

01:03:50
Speaker 3
Be sure to join me next time for more tools, tips and techniques you can use to look and feel your best and be built to last. Also, I’d love to connect with you and hear your thoughts on the podcast. Here’s how. First, subscribe to the podcast and leave an honest review. Second, take a screenshot of your review and third, text it to 813-565-2627. That’s 813-565-2627. When you do, I’ll reply using my brand new virtual jj.

01:04:28
Speaker 2
It’s my on demand virtual self built.

01:04:31
Speaker 3
From my books, talks and years of experience so I can interact with you directly. You’ll make my day and I can’t.

01:04:38
Speaker 2
Wait to hear from you. Thanks for tuning in and I’ll catch you on the next episode. Hey JJ here.

01:04:46
Speaker 3
And just a reminder that the well Beyond 40 podcast offers health, wellness, fitness and nutritional information that’s designed for educational and entertainment purposes only. You should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional. Make sure that you do not disregard, avoid or delay obtaining medical or health related advice from your healthcare professional because of something you may have heard on the show or read in our show notes. The use of any information provided on the show is solely at your own risk. You know, when we talk about menopause, the focus is almost always on hormones. But what I’ve learned is that’s only.

01:05:31
Speaker 2
Part of the picture.

01:05:32
Speaker 3
Because this phase of life doesn’t just affect your hormones, it affects how your brain works, your energy, how you feel day to day. And a big part of that comes down to your cells. Your cells rely on something called phospholipids. These are the building blocks of your cell membranes and they’re essential for how your brain functions, how your cells communicate, and how your body operates overall. As estrogen declines, your body’s natural production of key phospholipids can shift, which can impact things like mental clarity and overall resilience. That’s why I started focusing on supporting this more foundational layer. One of the things I added into my routine is Body Bio PC. It’s a phospholipid complex that helps support cell membrane health, brain function and liver function. Basically helping your body get building blocks. It needs to function well.

01:06:28
Speaker 3
And what I like about this is that it’s not just about chasing symptoms, it’s about supporting how your body works at a deeper level. So you’re supporting things like clearer thinking, better focus and feeling more like yourself again. And of course, Body Bio is known for really high quality practitioner trusted formulations. So if you’re in perimenopause or menopause and feel like something is still missing, this is definitely worth looking into. You can head to bodybio.com and use code JJVIRGIN20 for a discount.

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