[00:00:00] JJ: I’m J. J. Virgin, Ph. D. dropout, sorry mom, turned four time New York Times best selling author. I’m a certified nutrition specialist, fitness hall of famer, and I speak at health conferences and trainings around the globe, but I’m driven most of all. By my insatiable curiosity and love of science to keep asking questions, digging for answers, and sharing the information that I uncover with as many people as I can, and that’s where you come in.

[00:00:35] JJ: That’s why I created the Well Beyond 40 podcasts. To synthesize and simplify the science of health into actionable strategies to help you thrive. In each episode, we’ll talk about what’s working in the world of wellness, from personalized nutrition and healing your metabolism, to powerful aging and prescriptive fitness.

[00:00:56] JJ: Join me on the journey to better health so you can love how you look and feel right now and have the energy to play full out, you. Don’t miss an episode, subscribe now at subscribetojj. com to start unlocking your healthiest, most energetic self. There are compounds out there that you can use with confidence.

[00:01:21] JJ: Diet and lifestyle that are going to help rejuvenate your body. They work with your body to help make your body better. And you’re going to hear some stuff today that’s going to blow your mind. And what’s cool about this, as opposed to things like drugs, drugs get in there and they’re the sledgehammer that work to just kill you.

[00:01:39] JJ: You know, stop something. When you look at these peptides that we’re going to be talking about, they go in and rejuvenate. They go in and make your body work like it used to. So I’ve been really interested in them and I’ve been playing around with a couple of them with good results, BPC 157 and um, PeptiStrong.

[00:01:56] JJ: I’ve been using it from a company called Health Jebedi. So I wanted to get deeper into this. And the person who I’ve been listening to a lot online about it and who I had the pleasure to meet last year at the Health Optimization Summit is Natalie Nidham. She’s a holistic nutritionist and longevity educator and she has been really into bioregulator peptides for years now.

[00:02:19] JJ: You’re going to hear the whole story of how she got into them, pretty interesting, and so much so that she actually has a podcast, her longevity podcast, where she really focuses on the benefits of on them and shares her expertise on them. So, again, I am bringing the expert to you on this and you will learn how you can use these to maybe rejuvenate your thyroid, balance your blood sugar, help with reducing inflammation.

[00:02:44] JJ: Super cool stuff and it’s something that you can layer on top of what you’re already doing and cycle in for great results. So I will be right back with Natalie Stay with me.

[00:03:03] JJ: Natalie, welcome to the show. JJ, thank you for having me. I told you we’re diving right in. I surprised you. No, we’re going in. We’re going in. I am really excited about this topic. I’ve been stalking you on different podcasts. And I love all that you’re doing around peptides. And I thought we really haven’t talked much about them on the podcast, which is crazy since we’re about well beyond 40 and there’s such a cool thing and something I’ve been doing.

[00:03:33] JJ: So I’m excited to have you talk about them. How did you get into them?

[00:03:38] Nathalie Niddam: I am, I’ve, you know what it was? I was at a conference and I was exhausted. I’d been on the exhibitor floor, which is where I spend most of my time at these conferences. And I just needed to take a load off my feet. And so there was, there was a stage off to the side and there was an empty seat and I’m like, Oh, I’m going to go sit there.

[00:03:59] Nathalie Niddam: And so I sit myself down and I put down my bags and all of a sudden I can, you know, how you kind of hear a voice through the, Through the haze. And there’s a guy standing on stage talking about, yeah, and I’ve got this tan and I haven’t spent any time in the sun. And. And, and it’s, I got it from this stuff called Melanotan and then, which he didn’t say the stuff, he basically goes through the thing.

[00:04:22] Nathalie Niddam: And then he goes on and I’m kind of like, Oh, that’s kind of interesting. That’s weird, but interesting. And he doesn’t look like a carrot, so maybe there’s something

[00:04:30] JJ: to it. Yeah. It’s not like Charisse Turan at the, remember that? The Unfortunate Oscars. The Most Unfortunate

[00:04:37] Nathalie Niddam: Oscars. And so then, um, I, um, and then he starts talking, he throws up a slide and he’s talking about this Russian guy and this research on this stuff called epitalon.

[00:04:51] Nathalie Niddam: And it’s an old people study and how he gave it to these old people. And the next thing you know, it’s like 12 years later and the, the test subjects had 33 percent less mortality than the, than the control group. And I was like, that’s kind of interesting too. And then the NEN, he goes on to say, but that’s not all because they had better bone density and they had better happiness scores and they slept better and their melatonin production and their this and their telomeres.

[00:05:20] Nathalie Niddam: And I was like, okay, really? And the next thing he’s talking about BPC 157. And at this point, my jaw’s on the floor and I tap the guy’s shoulder in front of me. And I’m like, is this guy for real? Unbeknownst to me, this guy owned a compounding pharmacy. And he goes, honey, This is future of medicine. And I even forgave him for calling me honey.

[00:05:40] Nathalie Niddam: Cause I was like, Really? And that was it. That was my point of entry. Who was the guy? Dan Stickler. Oh, geez. You know him. I’m sure you know him. And it was Dan Stickler. And I was like, I was completely gobsmacked.

[00:05:56] JJ: Yeah. Yeah. He wandered into a great, into a great little lecture.

[00:06:01] Nathalie Niddam: Exactly. And he wasn’t, you know, he was on that side, it was the old Paleo FX.

[00:06:05] Nathalie Niddam: Oh, that’s amazing. It was on that side stage. Yeah. Yeah.

[00:06:08] JJ: Yeah. Yeah. I love, I love Dan’s wife, Mika, Mika, she’s a trip anyway. That’s incredible. That’s incredible. Okay. So you heard the lecture.

[00:06:21] Nathalie Niddam: Yeah. And that was like the tractor beam. And I heard Jean Francois Tremblay, who was the, who was the founder of CanLab Research, which is a research lab in Montreal.

[00:06:31] JJ: Okay. So you can just say this cause you’re Canadian. Cause I’m French. Are you French Canadian? Well,

[00:06:35] Nathalie Niddam: no, I’m French beyond Canadian. Here, let me say it in English, Jean Francois Tremblay is how most people would know him. And um, he was on a podcast and talking about, talking about peptides. And it’s so funny cause I’ve never done this before, but I’m like, Oh, he’s French.

[00:06:53] Nathalie Niddam: He lives in Montreal. I’ll bet you I could reach out to him and get him to talk to me. Because at this point I’m like, I’m all in, right? I’ve got the hook. Like I’m completely in. How

[00:07:04] JJ: long ago was this?

[00:07:05] Nathalie Niddam: It’s got to be five years, at least five years. Anyway, long story short, he became my mentor.

[00:07:12] JJ: Wow. And

[00:07:12] Nathalie Niddam: so I learned a ton from him.

[00:07:14] Nathalie Niddam: I started a Facebook community, which shockingly is still up because they’re going down. They’re taking, Meta’s taking down these groups like, Um, and, um, and then I started my podcast about a year later and, you know, the podcast was really a way to get people who knew more about this stuff to talk to me than I, you know, there were a lot of people who knew more than me.

[00:07:37] Nathalie Niddam: So I’m like, how am I going to get them to talk to me? I’m like, I know I’ll start a podcast and

[00:07:42] JJ: I’ll invite

[00:07:43] Nathalie Niddam: them and at the time, not that many people were talking about peptides. So they were just kind of stoked that anybody wanted to talk to them. So. That’s how it works. You’re

[00:07:53] JJ: a smart cookie

[00:07:54] Nathalie Niddam: there,

[00:07:55] JJ: Natalie.

[00:07:55] JJ: So here we are. Here we are. So just for someone going, well, what the heck are you even talking about? Explain what a peptide

[00:08:02] Nathalie Niddam: is. Yeah. So a peptide, peptide’s just another word for a small protein, right? So by definition, proteins we know are made up of enzymes. Amino acids, and I’m sure your audience knows exactly what amino acid is because otherwise they wouldn’t be allowed to listen to your broadcast.

[00:08:17] Nathalie Niddam: So amino acids, the building blocks of protein and peptides are 50 amino acids or fewer, right? So they’re by comparison, like you have, you have peptide, you have proteins in your body that are hundreds, if not thousands of amino acids long, and they’re all Fold it up into little origami shapes. So peptides are, generally speaking, when we’re talking about peptides, they’re fragments of those proteins.

[00:08:41] Nathalie Niddam: And it’s kind of like, they’re the, they’re the, they’re part of the active component. And so they’ve been isolated and identified as initiating certain, like, like they act as signaling molecules in the body. And so they initiate certain kind of, chemical or structural responses at a cellular level in the body.

[00:09:00] JJ: And people have heard of these because they’ve heard of GLP 1. So you’ve heard of peptides, but these are bioregular, regulator peptides. What, what is that meant by bioregulator?

[00:09:11] Nathalie Niddam: Right. So the bioregulators are like a subset of peptides, right? So you’ve got your GLP 1 agonist that you were just talking about.

[00:09:19] Nathalie Niddam: And then we have things like another one people might’ve heard about is BPC 157. Um, then there’s the melanotan I talked about earlier. Anybody who’s been into bodybuilding knows about melanotan because bodybuilders have been using those for a gajillion years, as well as the BPC. But the bioregulators are only two to four amino acids long.

[00:09:37] Nathalie Niddam: So they’re teeny, teeny tiny. To be very technical, we’re going to use that super technical term. They’re minuscule and what’s one of the features, and they go beyond being signaling molecules, they’re actually epigenetic switches. So what they do, because they’re so small, is they can cross the cellular membrane, they can get into the nucleus of the cell, and that’s where they basically bind to specific areas on the cell.

[00:10:02] Nathalie Niddam: on your DNA, and upregulate the production of proteins. And so in that way, they basically drive rejuvenation at a cellular level on a tissue specific basis.

[00:10:14] JJ: And just for everybody listening, these are the biggest threat to big pharma there could possibly be. So like Natalie said, hey, they’re like, meta is taking down all these things.

[00:10:30] JJ: It’s like, you see things like, is BP, um, C157 on or off right now? Like we just got a stash of it, but can you get it now or not get it?

[00:10:40] Nathalie Niddam: It’s, well, as, as far as your regulatory bodies are concerned, it’s off limits. Um, it’s, it’s not a bioregulator. Now, interesting about BPC is it’s more of a signaling molecule, but it also does affect gene expression, but more as like, it’s kind of like it’s hanging out more outside the cell and it’s doing it by sending, you know, Um, so, so the bioregulators were discovered and really researched over about three or four decades by a man in Russia by the name of Vladimir Kabinson.

[00:11:16] Nathalie Niddam: And so he was a young doctor in the military and Russian military back in the day. And his superiors came up to him and said, Vladimir. You know, we have a job for you. And he’s like, oh yeah, what would that be? And basically they’re like, you know, our astronauts are coming back from space, a hot mess. The submarine dudes are coming back from their nuclear missions, kind of not looking so good because of course in those days, nothing was really shielded that well, even probably isn’t even now.

[00:11:45] Nathalie Niddam: Um, and we need you to figure out a way to, you know, Undo the damage. And, and so that kind of sent him an, Oh, and then the best part was they kind of gave him a blank check and said, you can spend, well, in those days they had the money to spend, right? So you can spend whatever you need. We have factories filled with people who, you know, could use some good stuff.

[00:12:07] Nathalie Niddam: Uh, so off you go and off he went. And so he, he discovered these, these. These little tiny peptides that were so interesting because they occurred in every life form that he looked at. And, you know, we know in science when researchers find something that’s preserved across different species, that generally tells them it’s pretty important.

[00:12:34] Nathalie Niddam: And that’s kind of what led him to discover and develop this whole area of what we would call regenerative medicine around these little tiny proteins.

[00:12:45] JJ: Now, I’m assuming, because I will tell you, when I first heard about, uh, cerebrolysin, I could not find it anywhere and I had to order it using Using crypto from Russia, right?

[00:12:58] JJ: I didn’t think this through because I was getting it for my son to help regenerate his brain. Of course, I got it in these glass ampoules that were all in Russian, and then you were supposed to have it done in the IV. I was like, okay, well, this is crazy. Clearly not going to work well for me because I need to find someone to do this.

[00:13:15] JJ: Unless you

[00:13:16] Nathalie Niddam: need a filter on the needle. I mean, cerebral lysin is particular because cerebral lysin actually is an extract from pig’s brains. So it’s not even a bioregulator. There may be bioregulators in there, but it’s, it’s a whole other category. And these, this stuff is powerful medicine that’s actually used as medicine in countries like Russia.

[00:13:36] JJ: And that’s what I was going to ask. So in Russia, our Are these pretty common? Is this like standard of care to use these peptides?

[00:13:44] Nathalie Niddam: Well, I mean, I can’t answer the standard of care question because I don’t know, but I know that you can buy a lot of this stuff in drugstores.

[00:13:51] JJ: Wow.

[00:13:52] Nathalie Niddam: I don’t know about cerebral isin, but I know that you can buy bioregulators in drugstores.

[00:13:56] Nathalie Niddam: And so, It’s not that, I mean, if, if you have friends in Russia or Russian friends that kind of bounce back and forth, not that that’s an easy thing to do these days, um, you can get your hands on some pretty interesting stuff.

[00:14:09] JJ: Amazing. Well, what can we do here? In the U S and Canada. Now I will tell you full disclosure.

[00:14:15] JJ: My husband’s been using peptides now for years through our buddy, Dr. Tracy Gappin, but I know, you know, we’ve had some issues cause some of the things go on and off the market. We have a great compounding pharmacist. So we get a bunch of stuff, but, um, what are some of the. That you would want to be looking at if you were looking at aging powerfully and dealing with, you know, being a menopausal woman.

[00:14:39] Nathalie Niddam: Yeah. So that’s a great question. So the bioregulators are interesting because they originate in, so we make them when we’re young, right? Like they, we have them in our body and like all good things that must come to an end, we make less of them as we age. Right. So, so, you know, When Cavinson did his work, he figured out that he could isolate them from tissues, glands, and organs from animals, refine them, and either turn them into an injectable product, which is the hardest one to find, or turn them into a nutraceutical product.

[00:15:13] Nathalie Niddam: Kind of pill in a, in a capsule. Now those are the extracts. Then we have, we have the, the chem, the, the synthesized equivalents that are made in a lab. So we’re not going to talk about those for now, but the easiest way to get your hands on these right now is they are classified as nutritional supplements.

[00:15:33] Nathalie Niddam: The, the actual extracts that are orally bioavailable. And those we can buy. There’s, there’s a couple of, you know, there’s a couple of providers out there. There’s a guy in the UK, they’re, they’re profound health. They’re actually just setting up a warehouse in the States right now. Um. Yeah. There’s Dr. Kent Holthorff.

[00:15:53] Nathalie Niddam: He actually carries the Nature’s Marvels brand that Profound Health manufactures. And they had a very close relationship with Cavinson. So everything that they make had his seal of approval. So those are

[00:16:06] JJ: oral, not injectable.

[00:16:08] Nathalie Niddam: Yeah. And so they’re oral. So number one, there’s, they’re way less intimidating than having to run around and figuring out how to inject yourself.

[00:16:15] Nathalie Niddam: Cause you know, most people don’t love needles. Well,

[00:16:17] JJ: CPC 157. You know, you have to inject multiple times a day. I was like, Oh, I’m out.

[00:16:24] Nathalie Niddam: Yeah. Well, so with BP, but it depends what you’re using it for, right? BPC 157 is really interesting because it originates in gastric juice. It actually can be taken orally.

[00:16:35] Nathalie Niddam: The only thing is that the oral administration of BPC is much more effective for things like GI repair, GI issues. For the musculoskeletal benefits, for things like nerves, for the brain, BPC is generally better, to your point, used by subcutaneous injection. And then I would say, like, unless you’ve got something very, very intense going on, like a Crohn’s or colitis, usually for most people, two a day is safe.

[00:17:03] Nathalie Niddam: It’s, it’s good.

[00:17:05] JJ: Yeah, which is still If one is going to

[00:17:06] Nathalie Niddam: go there, which is still, you know, I mean, it’s, it’s, it’s, it’s an op It’s a hurdle.

[00:17:11] JJ: Yeah. I mean, I did, uh, prolo on my My luggage, my CrossFit luggage tear. And so I was like, oh, that’s what I’ll do. I will, I will do. And then I was like, oh no, I won’t . Oh, no, no, no.

[00:17:26] JJ: But I do take the oral, um, through Health Jevity.

[00:17:30] Nathalie Niddam: Yeah. I love his stuff.

[00:17:32] JJ: Oh my gosh. What about the Pep Strong? Do you use that? His Yes. I love that. Okay. Like my bff . Okay. Let’s, let’s definitely unpack those. So, so. Then it sounds like there’s probably a lot of options like Health Jevity where we don’t even have to go the route of these injectables through compounding pharmacies.

[00:17:51] Nathalie Niddam: Yeah. I mean, look, it depends on the peptide, right? So for the bioregulators, they’re all, Orally bioavailable. There are about five that, as a matter of fact, there’s five that you can’t even get as an injectable, right? Um, for the other pep, the longer chain peptides. So now we were into the BPC 157. Your audience may have heard about TB 500 or thymosin beta 4.

[00:18:13] Nathalie Niddam: There’s thymosin alpha 1. I mean, they have the sexiest names. We have to agree, right? Because they’re still classified as research chemicals. So some of those are orally bioavailable. Many of them are not. Many of them, as far as the body’s concerned, I don’t care how little it is, it’s still a protein, I’m going to chip chop it up and if you eat it, I’m chopping it up, you’re not getting the benefits.

[00:18:35] Nathalie Niddam: So what’s happening is I think the race that’s really going on right now is all of these scientists and researchers are looking for ways to get it, make it available to people without an injection. And there’s some pretty cool stuff coming down the pipes.

[00:18:51] JJ: And to be clear, the reason they’re trying to do that is so it’s not considered to be a drug.

[00:18:56] Nathalie Niddam: Mm,

[00:18:57] JJ: that too, because right now the challenge with these injectables is that, you know, they go on and off the market. Are there some injectables that you use and you would say are like ones you would definitely wanna look at for powerful aging, for regeneration, et cetera?

[00:19:15] Nathalie Niddam: So I am. I mean, the one, the, the big powerful aging one, if you will, is the pineal gland bioregulator.

[00:19:24] Nathalie Niddam: And it’s called epitalon. And somehow, I don’t even know how, it landed on that FDA no fly zone list. I, I, it, it actually blows my mind a little bit. Maybe because they, they heard somebody went to a lecture like I did and went, Oh no, no, no, no, no. We can’t be having that out there. So the good news is you can get it not as an injectable.

[00:19:44] Nathalie Niddam: You can get it as an oral supplement. And so, as an oral supplement, you would, if you were getting it from Nature’s Marvels, you would be buying the Pineal Gland Bioregulator. And its technical name is Endo Lutin. So the pineal gland bio regulator, the reason why it’s such a, it’s considered really powerful for a healthy aging is if you think about what the pineal gland does, it actually is your mast it, it regulates your circadian rhythm.

[00:20:13] Nathalie Niddam: And one of the reasons why the old people studies that Kavinson did were so transformative is the first one he did, he only gave them the pineal gland bioregulator. And just by giving them that he was able to say that they had a 33 percent lower mortality rate after six years, that after 12 years, then his control group who were given polyvitamins.

[00:20:34] Nathalie Niddam: And how old were these people? They were 65 to 75 years old. They’re right. That’s crazy. Like they were not. And these were oral. These were not injectable. So listen, so this is what’s interesting too. And this is where so much gets lost. Like from Russian translation to England, from over there to over here, there’s been mass confusion.

[00:20:55] Nathalie Niddam: I will say this. So the products that he was using were the injectable extracts from animals. So he, they were actually taking little itty bitty pineal glands from cows and smushing them up and doing whatever they did, just like the cerebral lysin and turning it into an intramuscular injection. And then the control group, so he was comparing, right, two different groups of people, same age, they were getting a polyvitamin injection.

[00:21:22] Nathalie Niddam: So they, everybody was getting an injection. Nobody knew what they were getting. So that’s why that study is pretty impressive. And so the pineal gland in a, in addition to managing your circadian cycle also regulates your melatonin production. And we’re all going to sit there and go, okay, well, so they slept better.

[00:21:39] Nathalie Niddam: Big whoop. Well, we know melatonin is, that’s a big whoop. Well, first of all, it’s a huge whoop. And secondly, melatonin is so much more than just about sleep. Right? It’s the most powerful antioxidant in your body. Like it, there’s tons of research on melatonin. On top of that, your pineal gland is your master endocrine regulator.

[00:21:58] Nathalie Niddam: So it has an impact on your whole hormone system. It also, the pineal gland also has an influence on the immune system. And the big, big nut here is that the pineal gland, by activating it through this, this bioregulator, it actually activates an enzyme called telomerase. And telomerase is an enzyme that regulates the length of the telomeres.

[00:22:23] Nathalie Niddam: And telomeres are those little ends on your DNA, which you guys have probably heard about. Every time your DNA replicates, you lose a chiclet off the end. If they get too short, they can’t replicate anymore and things start to look ugly. And so it’s. It’s like this, this kind of cocktail of benefits that tend, that is quite global to the body.

[00:22:44] Nathalie Niddam: And so that’s why the pineal gland bioregulator, I think is very, it’s critical to healthy aging.

[00:22:52] JJ: I wonder, so I did a lot of Dr. Joe work and I go to an event every year. And, you know, the big thing you learn there because you’re basically dinging the bell of the pineal gland. Yes. But the big thing that he talks about is how, you know, especially in the United States where we fluoridate, fluoridate?

[00:23:15] JJ: Is that how you say it? You put fluoride in water. Way better way to say it. I wasn’t going to be able to help you there. Sound right. Anyway, um, that you calcify the pineal gland. So I wonder if I wonder if some of this mechanism, is it like decalcifying the pineal gland? Like, I wonder what it’s doing. Who knows?

[00:23:35] Nathalie Niddam: I’ve asked the question and nobody’s been able to give me that answer.

[00:23:38] JJ: Yeah. Cause how would they be able to know? Like, how would you You’d have to

[00:23:40] Nathalie Niddam: get, you’d have to be able to image the pineal gland literally. Right. So I, um, and the other, and the truth of the matter is that the answer may be sitting in Russian literature.

[00:23:50] Nathalie Niddam: Because they’re not, they weren’t all that, they weren’t super diligent about sharing all their stuff. Right. And you know, what’s interesting about these bioregulators, if you, if I only had one, it would be the pineal gland bioregulator. The close second would be the brain one, which confusingly is referred to as pinealon.

[00:24:08] Nathalie Niddam: So you would think that pinealon is the pineal gland bioregulator, but no, pinealon is the brain bioregulator. And it, You know, from a central nervous system perspective, it’s a very important bioregulator. And especially if you’re a Joe Dispenza, um, aficionado, we understand that, that balancing the nervous system has everything to do with our function, with how we age.

[00:24:33] Nathalie Niddam: And even if you’re not Joe Dispenza, honestly, you like, we know this. And then, and then, You know, I used to say there was three. I would say there’s four because I’ve added that brain bioregulator in there. The next one would be the thymus gland bioregulator because our immune system is ultimately what takes us down.

[00:24:50] Nathalie Niddam: Whether it’s overactive, underactive, or going sideways, it’s the thing that’s, that kind of leads us down the path of aging. And then last but not least, we have the blood vessel bioregulator, because if we can help to restore function to the endothelium of blood vessels, everything goes better. We can deliver nutrients to the cells.

[00:25:11] Nathalie Niddam: We can remove toxins. Our heart can work better, all the things. And, and you know, after that, it becomes this stupid game of trying to pick your perf your favorite child. Because are you going to pick the heart or the liver? You know, are you going to pick the adrenal glands or the thyroid? I think we’d kind of be hard pressed not to say that they’re all kind of important.

[00:25:31] JJ: Well, you’d look at what your weaknesses are. Wow. So you’ve been taking these for five years now.

[00:25:39] Nathalie Niddam: About, uh, yeah, yeah. About not, not quite. No, I would say more like three.

[00:25:45] JJ: And how many are you taking?

[00:25:47] Nathalie Niddam: It depends. Like I don’t generally take more than three at a time and I’m not going to lie. There’ve been times where I’ve been like, you know what?

[00:25:54] Nathalie Niddam: I’m taking a break. I don’t just, I need a break. I don’t want to do this anymore. Is that

[00:25:58] JJ: a good way? Like, are, is it better to cycle these? Like, you know, what’s the recommendation?

[00:26:03] Nathalie Niddam: Yeah. I think everything needs to be cycled. Honestly, I don’t think there’s too many Except my estrogen.

[00:26:08] JJ: Don’t take that away.

[00:26:08] JJ: Well,

[00:26:09] Nathalie Niddam: no, except for that. Yeah. I was going to say there’s a few exceptions to that rule.

[00:26:13] JJ: Yeah.

[00:26:13] Nathalie Niddam: Um, but yeah, your estrogen, no, not touching your estrogen, promise. Um, but when it comes to peptides, for the most part, unless you have some kind of weird medical condition and you have a physician working with you telling you, you need this to continue to function for them.

[00:26:28] Nathalie Niddam: And particularly when it’s And I mean, think about what they’re doing. If they’re sending a signal to the body to rejuvenate, you shouldn’t have to keep hitting that button over and over and over and over again, right? You should be able to deliver the signal and then back off and then come back to it.

[00:26:44] Nathalie Niddam: So the way we do it is we typically cycle through the bioregulators and you know, I’ve got a, I’ve got a program in my, in my office. In a community that I manage where we’re doing a year of bioregulators programs. So I’m guiding people through cycling through the bioregulators over the course of a year.

[00:27:01] Nathalie Niddam: And sometimes if somebody is, you know, they’ve got major blood sugar issues or, you know, they have a, they’re particularly concerned about their brain or whatever the case may be, we’ll lean into those and bring them back more often. But at the, but bottom line, We’re, we might do, you know, when, when you’re reading the research that Cavinson wrote, if they were dealing with someone who had an actual issue they were trying to work on, what they would often do is start with a 30 day induction period, if you will.

[00:27:33] Nathalie Niddam: And after that, they would, might follow it up with like 10 days a month for a couple of months until things started to shift. Interesting. And the other interesting thing about the bioregulators is they play really well. Yeah. Cool. With medications. So you don’t have to, it’s not an either or, it’s a, it’s a this end,

[00:27:51] JJ: right?

[00:27:52] Nathalie Niddam: Because sometimes you need conventional medication. Sometimes the medication is required for a period of time, but what the medication doesn’t do is encourage a renewal, if you will, in the body, which the bioregulator does. Right.

[00:28:05] JJ: So these are, The difference with this is like a medication may block a symptom.

[00:28:12] JJ: This actually is regenerative. And this, this is what I think people are missing about GLP 1s. Like I look at people who are trying to lose weight and quite often their metabolic health is the limiter. For them being able to lose weight. I know that the, there are people out there say it’s just a calories thing.

[00:28:34] JJ: And I’m like, have you worked with someone who’s very metabolically damaged? Sorry. You know, it’s stupid, insulin resistant, you know, cause it’s, it’s more than that. Your body’s a bank account and chemistry lab and a history book. So we got a whole bunch of stuff going on there from toxins and trauma to, you know, insulin resistance and cortisol and estrogen to, you know, maybe some little bit of.

[00:28:58] JJ: Over at underestimating what you’re doing in terms of lifestyle. So

[00:29:01] Nathalie Niddam: yeah,

[00:29:02] JJ: no, all, all, all the above. But what it seems to me that I’m seeing with GLP ones, that’s so interesting is that they can come in repair, which it sounds like is kind of the hallmark of these. peptides is that they’re going in and doing repair work.

[00:29:19] Nathalie Niddam: Yeah. I mean, I would say the GLP 1s are a little different in a way, but I, but I, I hear what you’re saying. I think you’re right. And I think, I think the, and I think we agree on the GLP 1s. I think the biggest problem with GLP 1s right now is they become everybody’s step one. And sometimes they don’t go past step one.

[00:29:38] Nathalie Niddam: Because you

[00:29:39] JJ: should have to earn the right to use a GLP 1. It should be, okay, we’ve got you eating protein. We’ve got you lifting weights. You’re focusing on your sleep. Now you get to use GLP 1. So you use the least amount as you’re doing these things to help you heal and restore insulin sensitivity and get out of your metabolic black hole.

[00:29:57] Nathalie Niddam: Yeah, exactly. Like exactly right. And we’re going to go as slow as possible. Like we’re going to give you enough so that the needle is moving. But we don’t want the needle to go all the way off to the side here. We want to give your body time to adapt. We want your brain to have time to reset your set point.

[00:30:15] Nathalie Niddam: We want, you know, we want this to happen slowly and gradually so that we bring everybody along. We’re just not ripping fat off your frame because guess what? That’s an injury and it’s coming right back.

[00:30:27] JJ: Well, and it’s not just fat you’re ripping off if you’re doing it fast. Yeah.

[00:30:31] Nathalie Niddam: Yeah, exactly.

[00:30:32] JJ: Well, let’s pop back over to bioregulators.

[00:30:35] JJ: We’ll jump back and forth because we’re women and we can do that. We can do that. Um, so what are some of the things that you’ve seen, like you personally taking these bioregulators, like personal experience of what’s happened to you?

[00:30:47] Nathalie Niddam: Yeah, so for me, I’ve never I haven’t had a major issue, but what I’ve seen in my community, I have better stories about them than I do about me.

[00:30:57] Nathalie Niddam: Um, so some of the stories that I’ve seen that have really kind of given me pause, right? So I’ve seen this a couple of times now with women with thyroid issues. And one in particular, who’s in my, in my group who came in one day and said, guys, you are not going to believe this. So I’ve been hacking away at my Hashimoto’s for years with my naturopath.

[00:31:20] Nathalie Niddam: So she’s been doing all the work. She’s changed the diet. She’s, you know, she’s doing all the things and she couldn’t get, she just couldn’t move the needle. And she said, so I decided I was going to go buy the thyroid bioregulator and I was going to do 30 days of this bioregulator. And in her case, it was the last piece of the puzzle.

[00:31:40] Nathalie Niddam: That she needed. And she, she came back and she said, like, she, like her naturopath almost fell off her chair. Wow. She was like, holy jumping. Like your, your numbers look normal. Wow. Right. And so, but that is an unusual, cause I’ve had lots of people with thyroid issues, throw the thyroid bioregulator in. I would say typically if I was going to help someone who was working on a thyroid issue, it would be part of the equation.

[00:32:09] Nathalie Niddam: I would probably add in the adrenal bioregulator as well because those two glands are so inextricably linked and I would probably throw the central nervous system in there too. Right. So we’re hitting the HPAX and we’re, we’re going the whole way up and down. Um, another one that really moves the needle, which is really interesting is the prostate for men.

[00:32:31] Nathalie Niddam: So for, I had an elderly guy who was getting up to go to the bathroom like 500 times a night. Okay, I’m exaggerating, maybe four, but four is disrupted sleep, like, it’s a pain. And, uh, so I put him on the prostate bioregulator with the blood vessel bioregulator. He did 30 days, and then we had him do 10 day cycles after that.

[00:32:53] Nathalie Niddam: And, lo and behold, doesn’t my phone ring after a couple months going, you’re not going to believe this. I’m going to the bathroom once and I’m pretty much sleeping through the night. So that’s another one. Now, again, you want to make sure that you’ve knocked out all the negative, you know, all the bad things that could be at play here.

[00:33:14] Nathalie Niddam: And once we know that it’s just benign prostate hyperplasia or whatever the case may be, now we can start to think about, could the bioregulator be a Um, what’s the, uh, I’ve had people’s liver enzymes come down from using the liver bioregulator. I’ve seen blood sugar control get better with the pancreas, but I want you guys to hear this.

[00:33:36] Nathalie Niddam: In every case, they were also doing all the other things. The liver person wasn’t sitting there pounding alcohol or doing whatever and watching their liver enzymes drop. The person whose pain, whose blood sugar numbers started to normalize, was also working on their diet, but they’d been doing that forever and just weren’t making any progress and bringing that bioregulator in just seemed to be the final little push that they needed to start to get things to move in the right direction.

[00:34:05] JJ: Yeah. I think that’s the difference between a drug, which is a sledgehammer and it’s just going to just attack whatever it is. Whereas this is just one piece.

[00:34:18] Nathalie Niddam: Yeah.

[00:34:18] JJ: Of the assessed.

[00:34:19] Nathalie Niddam: It’s the training wheels on the bike. You know, when your little kid’s learning to ride a two wheeler, if you ever did that, like, you know, they’ve got those little training wheels and at first they wobble and they use the training wheels a bit and then eventually they don’t need them and maybe once in a while the wheel, and then eventually you take them off.

[00:34:35] Nathalie Niddam: You don’t need them. So that’s the idea.

[00:34:37] JJ: So these ones that you’re using right now, can people in the United States get them now, or is it going to be? Mm

[00:34:43] Nathalie Niddam: hmm, a hundred percent, and you don’t need to use crypto.

[00:34:47] JJ: Cool. Yeah, you don’t have to, well, you know, when we were getting them, we were signing up to do, they were said, not for human use, right, for animal use only, part of a test subject.

[00:34:59] JJ: I’m like, okay, you know. Here we go, honey. We’re going in. Let’s go. We’re now test rats. Okay. We’re now lab rats. We’ll try it. All right. This all makes sense. Let’s just, let’s flip gears just for a moment. Cause I would love to address, um, you know, the GLP 1s. Since you’re coaching a lot on these bioregulators, are it does, do the GLP 1s come into this conversation at all?

[00:35:26] Nathalie Niddam: Sure. I mean, if somebody has got a lot of weight to lose. Um, you know, if, if, if, if that’s what they need, you know, it’s like you said earlier, like on the one hand, we don’t want them to be the one stop because you’re, you’re shooting yourself in the foot. But on the other hand, for someone who’s been, we have to accept that people have broken their metabolisms.

[00:35:49] Nathalie Niddam: Like they’ve, they’ve been yo yo dieting. They’ve been abusing their bodies or in the case sometimes with women with, as they go through menopause, like world goes to hell in a hand basket. They pack on the, I call it the magic 10, right? It just shows up overnight. You didn’t change anything and you wake up one morning, you look down and you’re like, what just happened?

[00:36:08] Nathalie Niddam: I know

[00:36:09] JJ: if anything, you’re doing like, More exercise, restricting more. You’re like, what is going

[00:36:14] Nathalie Niddam: on? This is not okay.

[00:36:16] JJ: Whose body is this?

[00:36:18] Nathalie Niddam: Exactly. You know, and I haven’t changed my diet, which is part of the problem because nobody tells us. That we’re about to become insulin resistant when we weren’t, right?

[00:36:27] Nathalie Niddam: So, so the GLP 1, it’s, it’s a bit like BPC 157 with gut issues. There, there are compounds that can move the needle for people even before they can move it by themselves. And it starts like for someone who’s carrying around an extra 50 pounds, if they can start, start dropping weight. All of a sudden they have more energy.

[00:36:49] Nathalie Niddam: All of a sudden they can move more. All of a sudden their inflammation has dropped a little bit. They’re not as achy. They want to exercise. So I think it’s, it’s how we use them and it’s the promise that we make, which first of all, we don’t make promises, but it’s the, the promise that’s being put out there right now is use this and you’ll be fine.

[00:37:10] Nathalie Niddam: And the real promise should be, this is something that is going to give you back that competitive edge. It’s going to give you the ability to help your body to do the work so that you can get to yourself to a point where you’re healthier, you’re fitter, you’re leaner, you’ve got more muscle. You’ve, you’ve taken the opportunity of not caring as much about food so that you can recalibrate your taste buds and learn how to eat normal food again.

[00:37:36] Nathalie Niddam: And now we’re in a world where we can start to help people hit their goals and now wean them off, maybe, or maybe they stay on a baby baby dose because they just need it. But, you know, I’ve had someone else say to me today, so they’re going to have to be on GLP 1s for the rest of their life. And I’m like, no, they won’t.

[00:37:53] Nathalie Niddam: I mean, some people might, but a lot of people won’t. But even if they were,

[00:37:58] JJ: like you look at it and go, all right, someone going through menopause, Estrogen drops, inflammation goes up, they become insulin resistant, cortisol goes up, and this could, and now estrogen is dropping so it’s hard to build muscle, this could Drop the inflammation, improve the insulin sensitivity, help them build muscle because it actually can.

[00:38:19] JJ: And so they have that chance. If it was someone who’s obese or morbidly obese, think of the polypharmacy that they’re on. And so when I hear the argument, Oh, they might have to be on this for life. I’m like, but they were going to be on all these other things for life. So all of a sudden they get off their blood pressure medication, cholesterol medication, you know, all these, their, their, you know, insulin.

[00:38:43] JJ: All these other things, and they’re on one thing, low dose cycling. How is that a problem? And that’s bad? I’m missing, I’m, I’m missing, I’m missing the problem here.

[00:38:55] Nathalie Niddam: Help me. Help me understand this. Because they’re not taking that statin anymore that’s causing muscle weakness so that their bicep, Tendon will rupture when they try to pick up the

[00:39:03] JJ: wrong thing.

[00:39:04] JJ: Exactly. You’ve got something that’s actually helping them build muscle. So in it’s, that’s a terrible thing. Yeah. I was just on a panel recently at an event where it was, I was the middle ground. I was like, they put me in the middle. They put the scientists over here who were talking, you know, the positives about it.

[00:39:21] JJ: And they put, uh, Jillian Michaels and Kelly means. And I actually got called a liar and full of shit. And I was like, you did not never, never have I ever, I actually go listen to everything I’m saying because I’m not an MD. I actually have all the research with me. So I’m happy to share all this with you.

[00:39:39] JJ: And so no, I’m not a liar or full of shit. Thank you very much. But it was pretty interesting because my whole thing was. People, I’ve, I’ve worked in weight loss for 40 years. When people get to a certain point where their weight loss resistance, they’ve got such metabolic damage. They’re deep in a hole they’ve got to dig out of.

[00:39:56] JJ: If you could throw them just a little rope to help them start to get out of the hole as they’re doing the other good things, it’s great, you know, but sorry, Jillian, you actually work with people on a ranch. When I worked in, in TV, We at Dr. Phil didn’t have them on a ranch, we had them in real life. So I saw the difference between being able to tightly control people or sending them out into the wild.

[00:40:20] JJ: And you know, the reality is it’s a challenge.

[00:40:22] Nathalie Niddam: Well, and what happens to those ranch people when they leave the ranch? Well, we know what

[00:40:26] JJ: happens to the ranch people when they leave the ranch.

[00:40:29] Nathalie Niddam: I know, exactly, exactly. But that’s what I mean, you know, like that’s your long term success. Like that’s just, I don’t, I don’t, I don’t, I mean, there was, there’s some doctor recently, I’m sure you’ve seen this, put up a post saying that GLP ones are going to eat.

[00:40:43] Nathalie Niddam: Not only are they going to eat your fat, they’re going to eat your muscle and your heart is a muscle. So it’s going to eat your heart. And I’m like, come on, like, what, who’s paying you to say this? Like that’s, well, they’re not

[00:40:53] JJ: eating anything. They’re not like number one, there’s no Pacman. Number one. And number

[00:41:00] Nathalie Niddam: two, like I’m not a doctor.

[00:41:04] Nathalie Niddam: Either, and, but we know, we understand the mechanism of action here. Like it’s, it’s, we need to get rid of this dogma that’s so prevalent and, and bring back a more nuanced message that helps people to understand these are such a powerful, powerful tool, but you got to learn to use them properly. And you will get to live happily ever after.

[00:41:24] JJ: Yeah, well I love the way you’re approaching this because it’s like, okay, do all the things and then here are some things for the areas that need some rejuvenation. Yeah. That you can cycle in and do. I’m like, this is fabulous. And I didn’t know, and this is why I wanted you selfishly to be on the show, like I’ve been using the PeptiStrong one, and I also use the oral BPC 157 because I was too big of a baby to inject myself twice a day.

[00:41:49] JJ: I literally do a testosterone injection every other week and that’s it. Tim has to do it, and I go do the cold plunge, then I get out, then he has to do it, like, it’s a whole thing. It’s a whole thing. It’s

[00:41:59] Nathalie Niddam: like,

[00:42:00] JJ: I’m a big baby about these

[00:42:01] Nathalie Niddam: things. But you get into the cold plunge, so that’s pretty good.

[00:42:03] JJ: Right?

[00:42:04] JJ: Like, when he was icing me down, I’m like, why wouldn’t I just do this after I get out of the cold plunge? I’m just saying. No. Duh, anyway, I know you have a guide you’ve written about this. So in the guide, does it tell where to get these things to?

[00:42:21] Nathalie Niddam: Um, which ones? Like, so the bioregulators that, that’s, that’s readily available.

[00:42:26] Nathalie Niddam: That’s on my website. I’ve got a whole page. I mean, cool. My, my. I have a new website coming. I’m so excited.

[00:42:33] JJ: It means right now it’s you’re in that, that terrible space. You’re in that space where you

[00:42:37] Nathalie Niddam: look at your old

[00:42:38] JJ: website. Oh my God. Shame. And then I hate to tell you this, but your website’s done and you love it and it’s so beautiful.

[00:42:46] JJ: And then a couple of months later, you’re like, Oh, shoot. Like, that’s what I, I was like, oh shoot, I thought I just did all this and now this all needs to be redone again. It’s like it’s.

[00:42:54] Nathalie Niddam: Nope, nope. I’m, I’m, right now I’m still in the anticipatory phase, so I’m, I’m stittin with that.

[00:42:59] JJ: Okay, cool. It’s, it’s like house remodeling, but you get it all remodeled and then you’re like, oh.

[00:43:03] Nathalie Niddam: Yeah. Why did we pull up the floor? Why did we put in a new, all these new kitchen cabinets and not change the floor? Like whose idea was that? Um, anyway, but so, so the oral, the oral peptides, the bioregulators, all that is on the website. I mean, look, because of regulatory issues, the injectables are, it’s a very gray zone.

[00:43:24] Nathalie Niddam: So there’s a couple of research labs that I, I trust and have worked with in the past. Um, and. You know, in the communities, in the group, like people share about all this stuff, we talk about it. I think, I think to be honest, people need to be cautious and they need to use their good judgment here.

[00:43:47] JJ: Yeah.

[00:43:48] JJ: Don’t, don’t do what I did. Do not order the, the glass ampoules from Russia that you can’t, then I couldn’t do anything with it anyway. So. Well, and

[00:43:55] Nathalie Niddam: you don’t know how to use them, right? Yeah, I didn’t know how to

[00:43:57] JJ: use them.

[00:43:57] Nathalie Niddam: And I mean, I can’t even begin to tell you how often in the Facebook group we get a post from someone saying, well, I just spent 500 and here’s, and they post a picture of all the things they bought.

[00:44:08] Nathalie Niddam: So now what do I do with them?

[00:44:12] JJ: Who does that? We don’t even know what’s in there. Well, the fact that we can use these orals is fantastic. Like, I mean, anyway, wouldn’t we want to? And again, all I’ve been messing with is, uh, the Health Jevity company because I got turned on to the PeptiStrong. Yeah. Oh, yes.

[00:44:29] JJ: But I’m. Excited to dive in more now that I’ve heard this. So,

[00:44:34] Nathalie Niddam: yeah, no, I mean the, you know, there’s some really, there’s such interesting information and there’s, there’s one peptide called thymosin alpha one and it’s an immune peptide and it’s actually, um, it’s, it’s an approved drug in about 40 different countries.

[00:44:51] Nathalie Niddam: Just not Canada and the U. S. Isn’t it so crazy? Which is so tragic because what it does is it supports the innate immune system. And so, you know, if you want to talk about giving of like, if you wanted to talk about the evil vaccine world word, and we can talk about the fact that elderly people, their immune system is so exhausted half the time, they can’t mount An immune response to a vaccine to make it useful.

[00:45:18] Nathalie Niddam: Well, there’s a, there’s a study out there that shows that if they use thymus and alpha 1 as the adjuvant, it actually supports the body’s immune reaction so that the vaccine actually works for them. Now I’m not saying anybody should go out and get a vaccine, I’m, you know, I don’t want to have any part of that conversation.

[00:45:35] Nathalie Niddam: I’m not promoting vaccines. All I’m saying is there’s really interesting information about other countries that use these compounds as medications that for some reason, we’ve just got our heads in the sand in these kind of here saying, no, no, no, we don’t want to hear about it for some reason. We just don’t think it’s okay.

[00:45:54] Nathalie Niddam: And I’m hopeful that. In the not too distant future, there’s going to be more openness about this stuff because It

[00:46:02] JJ: seems like we’re going that direction.

[00:46:04] Nathalie Niddam: It seems that way, right? I mean, with BPC 157, it has so many potentials. It affects so many different systems of the body positively. Now it doesn’t mean that some people might not have a negative reaction to it.

[00:46:17] Nathalie Niddam: It does and can happen. So that means that we need to bring it out of the shadows. We need to bring it into the light. We need to do the research. We need to Or at the very least allow all of these functional physicians who’ve been working with this stuff to be open about it, to present their work, to, to talk about it with each other so that we can start to learn more.

[00:46:39] Nathalie Niddam: I mean, this is, this is an opportunity. Like these are, these are compounds that really work with our physiology instead of blocking it or stifling it. So this is the stuff we want to really lean into. Now you have a guide, right, that you go through all of this? So in my membership community, if people join as an annual member, they get, they get access to the peptide crash course, I

[00:47:03] JJ: call it.

[00:47:04] JJ: We’ll make sure we put all of this information in the show notes and I’m going to put it now. Natalie’s name is not spelled the way you would think it’s spelled. So jjvirgin. com forward slash Natalie with an H. Right? N A T H A L I E.

[00:47:19] Nathalie Niddam: Yes, you even put the H in the right place. So it sounds like

[00:47:22] JJ: Nathalie.

[00:47:23] Nathalie Niddam: Yes, because French people have no clue what to do with H’s. They don’t pronounce them. So it’s like this decorative letter. They’re kind of like, I don’t know what I’m going to do with it. Stick it into places and then, and then poor English speaking people try to pronounce it and, you know, it’s.

[00:47:41] JJ: Well, the only reason is I’ve, I’ve met you and I knew you.

[00:47:43] JJ: So I was like, I know it’s not Nathalie.

[00:47:45] Nathalie Niddam: Yes. But you know, many people have called me Nathalie. Oh,

[00:47:49] JJ: I’m sure.

[00:47:49] Nathalie Niddam: Yeah. Of course. It’s been done. Yes.

[00:47:53] JJ: I know we’re going to see each other in a week.

[00:47:56] Nathalie Niddam: I can’t wait.

[00:47:57] JJ: Now, are you in the biohacking movie or are you in the shield? I’m in the movie. The biohacked one.

[00:48:02] Nathalie Niddam: I’m I I’m in the Biohack Yourself movie.

[00:48:04] Nathalie Niddam: Cool.

[00:48:04] JJ: So, and you’re,

[00:48:05] Nathalie Niddam: you’re heading Up shield, which is amazing. I’m the

[00:48:08] JJ: Shield Movie. This, these are two documentaries that have like a whole host of awesome people that the lollies have put together. So we are gonna be at this premier at a four m in a week together, which is super fun. So, super

[00:48:23] Nathalie Niddam: exciting.

[00:48:23] Nathalie Niddam: Yeah.

[00:48:24] JJ: Yes. Like, it’ll just be fun to see everybody there. A hundred percent. This has been amazing. I am going to try more things beyond just PeptiStrong and some BPC. Well, you know, it’s like anything muscle, you know, it’s like. Line me up. It’s like my dogs with chicken, you know, more muscle, like I’ll do it, you know.

[00:48:46] JJ: Yeah, I’m going to do a little thyroid experiment next because this is interesting stuff. I’ll report back in. So thank you. Thank you. I appreciate you. I’m looking forward to seeing you in, in real life here soon.

[00:48:56] Nathalie Niddam: Thank you so much, JJ. It was a pleasure.

[00:49:03] JJ: Be sure to join me next time for more tools, tips, and techniques you can incorporate into everyday life to ensure you look and feel great and are built to last. Check me out on Instagram, Facebook, and my website jjvirgin. com and make sure to follow my podcast at subscribetojj. com so you don’t miss a single episode.

[00:49:26] JJ: And hey, if you’re loving what you hear, don’t forget to leave a review. Your reviews make a big difference in helping me reach more incredible women just like you to spread the word about aging powerfully after 40. Thanks for tuning in. And I’ll catch you on the next episode.

[00:49:51] JJ: Hey, JJ here. And just a reminder that the Well Beyond 40 podcast offers health, wellness, fitness, and nutritional information that’s designed for educational and entertainment purposes only. You should not rely on this information as a substitute for, nor does it replace professional medical advice, diagnosis, or treatment.

[00:50:09] JJ: If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional. Make sure that you do not disregard, avoid, or delay obtaining medical or health related advice from your healthcare professional because of something you may have heard on this show or read in our show notes.

[00:50:25] JJ: The use of any information provided on this show is solely at your own risk.

 

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