How healing your microbiome fights disease, boosts brainpower, and redefines your healthspan

“Our gut microbiome had a big deal in protecting us and teaching the immune system who’s a good guy, who’s a bad guy.” – Dr. Steven Gundry

I welcome back controversial cardiologist-turned-nutrition expert Dr. Steven Gundry to discuss his latest book, Gut Check, where he shares groundbreaking insights on how our microbiome influences everything from mental clarity to longevity. As a former heart surgeon who now sees patients six days a week, Dr. Gundry revealed why both neurologists and cardiologists are now obsessed with gut health—because as Hippocrates said 2,500 years ago, “All disease begins in the gut.” We explored how leaky gut leads to systemic inflammation and accelerated aging, plus practical ways to repair your gut barrier and restore your internal “tropical rainforest” of beneficial bacteria. Dr. Gundry also challenged popular “Blue Zone” myths, arguing that longevity hotspots aren’t plant-based paradises but rather communities of active people consuming fermented foods, animal products, and engaging in consistent physical activity on hilly terrain.

Get Dr. Gundry’s new book Gut Check: Unleash the Power of Your Microbiome to Reverse Disease and Transform Your Mental, Physical, and Emotional Health

What you’ll learn:

  • Why leaky gut is the hidden driver behind autoimmune disease, Hashimoto’s, eczema, depression, and brain fog
  • How the health of your gut barrier directly impacts your longevity and quality of life
  • The crucial role of butyrate and why 80% of your colon cells depend on it for nourishment
  • Why simply taking probiotics isn’t enough—you need fermented foods and prebiotics together to rebuild gut diversity
  • Simple ways to increase beneficial short-chain fatty acids through foods like vinegars and low-sugar kombuchas
  • The truth about Blue Zones and why many longevity hotspots actually feature sheep herders eating fermented dairy and cured meats
  • How “exercise snacking” throughout the day on hilly terrain contributes to longevity

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Resources Mentioned in this episode

Gut Check by Dr. Gundry

The Gut-Brain Paradox by Dr. Gundry

GundryMD Bio Complete 3™

Dr. Gundry on Instagram

Dr. Gundry on YouTube

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